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Research in Novel Immune Adjuvants

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 30 March 2025 | Viewed by 33

Special Issue Editor


E-Mail Website
Guest Editor
Faculty of Health Sciences, University of Macau, Taipa, Macao
Interests: precision immuno-oncology; biomaterials; nanobiotechnology; nano-bio effects; cancer nanomedicine; cancer theranostics

Special Issue Information

Dear Colleagues,

Despite essential improvements being made in vaccine immunogenicity, adjuvants are always studied with an awkward lag compared to vaccine discovery. Over a long period of time, a very limited number of adjuvants have been clinically approved, all of which are associated with aluminum salts, monophosphoryl lipid A, and oil emulsions. However, increasing evidence has demonstrated that adjuvants alter the quantity and quality of adaptive immune responses through activating innate immunity. Those immune responses differ by population and may have distinct safety risks. Recent innovations in adjuvant research have intersected with formulation science, immunology, toxicology, biology, etc. More importantly, human in vitro models, immuno-engineering, and novel delivery systems are being proposed to identify biomarkers of safety and adjuvanticity. Immunological adjuvants exploited through adopting novel multidisciplinary approaches therefore hold promise to become precision adjuvants, optimizing science and safety.

Dr. Bei Li
Guest Editor

Manuscript Submission Information

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Keywords

  • adjuvants
  • vaccine
  • immunology
  • toxicology
  • biology

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Published Papers

This special issue is now open for submission.
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