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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Functional Nanomaterial: Design, Synthesis and Applications

edited by

Fariborz Tavangarian

submission deadline 27 Jun 2024 | 4 articles | Viewed by 4386 | Submission Open

Keywords: functional organic nanomaterials; design; synthesis; applications; drug delivery; biosensors; catalysis; energy conversion

(This special issue belongs to the Section Molecular Nanoscience)

Advanced Research on the Adrenal Gland and Hormones

edited by Marcin Ruciński

submission deadline 27 Jun 2024 | 1 articles | Viewed by 494 | Submission Open

Keywords: bioactive peptides; adrenal gland; adrenocortical carcinoma; HPA axis; G protein-coupled receptor; hormones; steroidogenesis

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Bioactive Nutrients Promoting Health through Gut Microbiota 2.0

edited by

Baojun Xu

and

Matteo Bordiga

submission deadline 28 Jun 2024 | 8 articles | Viewed by 39885 | Submission Open

Keywords: phytochemicals; complex carbohydrates; bioactive nutrients; gut microbiota; prebiotics; probiotics; inflammation; molecular mechanisms; human health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research in Prebiotics, Probiotics and Postbiotics

edited by

Julio Villena

and Haruki Kitazawa

submission deadline 28 Jun 2024 | 7 articles | Viewed by 9548 | Submission Open

Keywords: probiotics; prebiotics; postbiotics; symbiotics; immunobiotics; functional foods; health improvement; mucosal immunology; microbiota

(This special issue belongs to the Section Molecular Microbiology)

Natural Bioactive Compounds for Human Health 2.0

edited by

Chun-Tao Che

and

Hongjie Zhang

submission deadline 28 Jun 2024 | 6 articles | Viewed by 8899 | Submission Open

Keywords: natural bioactive plant products; biological and pharmacological activity; natural plant drug discovery and development; nutraceuticals; botanical dietary supplement

(This special issue belongs to the Section Molecular Pharmacology)

Nonalcoholic Fatty Liver Disease/Metabolic Associated Fatty Liver Disease: New Insights 3.0

edited by

Andrea Dalbeni

and

Alessandro Mantovani

submission deadline 28 Jun 2024 | 5 articles | Viewed by 8668 | Submission Open

Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); fatty liver; cardiovascular disease

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Genetics- and Genomics-Based Crop Improvement and Breeding : 2nd Edition

edited by Jian Ma

submission deadline 28 Jun 2024 | 8 articles | Viewed by 7570 | Submission Open

Keywords: crop; germplasm; genetics; genomics; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Characterization of Extracellular Vesicles in Disease

edited by

Verena Tretter

submission deadline 28 Jun 2024 | 3 articles | Viewed by 6629 | Submission Open

Keywords: extracellular vesicle; exosomes; microvesicles; vesicle cargo

(This special issue belongs to the Section Molecular Biology)

Molecular and Structural Research Advances in Model Plants

edited by

Ioannis-Dimosthenis Adamakis

submission deadline 28 Jun 2024 | 5 articles | Viewed by 6103 | Submission Open

Keywords: A. thaliana; plant biology; model organisms; plant models; non-model plant models

(This special issue belongs to the Section Molecular Plant Sciences)

Plant Resilience Mechanisms for Coping with Environmental Stresses: Paving the Path to a Sustainable Future

edited by

Silvia Celletti

submission deadline 28 Jun 2024 | 3 articles | Viewed by 4350 | Submission Open

Keywords: antioxidants; drought tolerance; growth patterns; morphological adaptations; physiological changes; pathogen defense; protective proteins; root system development; stomatal closure; stress signaling pathways

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular and Translational Medicine 2.0

edited by

Mariarosaria Boccellino

submission deadline 28 Jun 2024 | 4 articles | Viewed by 3749 | Submission Open

Keywords: molecular pathology; biomarkers; signature transduction; cell signaling; molecular mechanisms; translational research; pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cytokines: From Cancer to Autoimmunity 2.0

edited by

Lyuba Dineva Miteva

submission deadline 28 Jun 2024 | 2 articles | Viewed by 3353 | Submission Open

Keywords: cytokines; cancer; autoimmunity; inflammation; gene expression regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Notch Signaling in Health and Disease 2.0

edited by

Paola Maura Ticarico

and

Sergio Crovella

submission deadline 28 Jun 2024 | 3 articles | Viewed by 2986 | Submission Open

Keywords: dermatological diseases; Notch signaling; keratinocytes; inflammation; autoinflammation; differentiation; keratinization; proliferation

(This special issue belongs to the Section Biochemistry)

Molecular Research of Hepatocellular Carcinoma

edited by

Kuo-Shyang Jeng

submission deadline 28 Jun 2024 | 2 articles | Viewed by 2822 | Submission Open

Keywords: hepatocellular carcinoma; liver inflammation; signaling pathways; novel markers; genetic factors; target therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism in Multiple Sclerosis and Related Disorders 2.0

edited by

Hans-Peter Hartung

Giancarlo Comi

and Kazuo Fujihara

submission deadline 28 Jun 2024 | 2 articles | Viewed by 2750 | Submission Open

Keywords: neurodegeneration; multiple sclerosis; NMOSD; MOGAD; disease modifying treatments

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research for Castration Resistance Prostate Cancer

edited by

Virginie Firlej

submission deadline 28 Jun 2024 | 1 articles | Viewed by 2496 | Submission Open

Keywords: prostate cancer; castration-resistant prostate cancer; therapy resistance; biomarkers; androgen receptor; new therapies; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Protective Immune Response to Virus Infection and Vaccines

edited by Zhifang Zhang

submission deadline 28 Jun 2024 | 2 articles | Viewed by 2139 | Submission Open

Keywords: pathogenic virus; zoonotic virus; vaccine; immune response; virus– host interaction

(This special issue belongs to the Section Molecular Immunology)

Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0

edited by

Elvira Rozhina

and

Svetlana A. Konnova

submission deadline 28 Jun 2024 | 2 articles | Viewed by 2117 | Submission Open

Keywords: magnetic nanoparticles and targeted drug delivery; magnetic nanoparticles as instruments for nanotopography; magnetic nanoparticles for bioimaging; magnetic nanoparticles for cell and biomolecule separation; magnetic nanoparticles and non-invasive imaging; magnetic nanoparticles and nanocomposites

(This special issue belongs to the Section Molecular Nanoscience)

Mucopolysaccharidoses: Diagnosis, Treatment and Management 4.0

edited by

Shunji Tomatsu

Grzegorz Wegrzyn

and Roberto Giugliani

submission deadline 28 Jun 2024 | 1 articles | Viewed by 2074 | Submission Open

Keywords: mucopolysaccharidoses; glycosaminoglycans; proteoglycans; lysosomal dysfunction; cell function; metabolic disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Natural Products in Non-alcoholic Fatty Liver Disease

edited by

Saioa Gómez-Zorita

and

María P. Portillo

submission deadline 28 Jun 2024 | 1 articles | Viewed by 1993 | Submission Open

Keywords: fatty liver; steatosis; steatohepatitis; hepatocarcinoma; non-alcoholic fatty liver disease; inflammation; fibrosis; oxidative stress; liver injury; active biomolecules; natural products; food; precision nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Research on Macrophages in Human Health and Disease

edited by

María Martínez-Esparza

submission deadline 28 Jun 2024 | 1 articles | Viewed by 1676 | Submission Open

Keywords: macrophages; phenotype; plasticity; inflammation; molecular mechanisms; signaling pathways; human disease; immunopathology; immunotherapy; target identification; natural compounds; drugs

(This special issue belongs to the Section Molecular Immunology)

Developing Methods and Molecular Basis in Plant Biotechnology

edited by

Wojciech Makowski

and

Mateusz Labudda

submission deadline 28 Jun 2024 | 1 articles | Viewed by 1578 | Submission Open

Keywords: plant biotechnology; plant genetics; plant proteomics; plant metabolomics; stress

(This special issue belongs to the Section Molecular Plant Sciences)

Beyond Antioxidants and Analgesics: From Natural Compounds to Synthetic Derivatives

edited by

Antonella Brizzi

and

Federica Pessina

submission deadline 28 Jun 2024 | 1 articles | Viewed by 1091 | Submission Open

Keywords: pain; oxidative stress; inflammation; bioactive compounds; antioxidant

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Drug Design and Development for Neurological Diseases

edited by

Alicja Nowaczyk

and

Grzegorz Grześk

submission deadline 28 Jun 2024 | 1 articles | Viewed by 1040 | Submission Open

Keywords: neurological disorders and their therapies; molecular modeling; synthesis and structural analysis; neurotransmitters ligands; mechanism of action; drug repurposing

(This special issue belongs to the Section Molecular Pharmacology)

New Advances of the Molecular Mechanisms of Gonad Development, Gametogenesis, and Fertilization

edited by

Kenji Murata

submission deadline 28 Jun 2024 | 1 articles | Viewed by 838 | Submission Open

Keywords: primordial germ cells; sex differentiation; extensive epigenetic reprogramming; Fertilization; oogenesis; spermatogenesis; vertebrate; imvertebrate; Sperm-egg interaction; folliculogenesis

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Human Stem Cells

edited by

Carmen Ciavarella

and Sabrina Valente

submission deadline 28 Jun 2024 | 1 articles | Viewed by 747 | Submission Open

Keywords: stem cells; mesenchymal stem cells; miRNA; differentiation; self-renewal; inflammation; transcription factors; senescence; extracellular vesicles

(This special issue belongs to the Section Molecular Biology)

The Roles of Photodynamic Therapy in Tumors and Cancers

edited by Jianyong Liu

submission deadline 28 Jun 2024 | 1 articles | Viewed by 553 | Submission Open

Keywords: photodynamic therapy; PDT; photodetection; photosensitizers; photosensitizing agents; reactive oxygen species; molecular mechanisms; cell necrosis; apoptosis; singlet oxygen; synergetic therapy; combination therapy; delivery vehicles; immunophototherapy; nano-photosensitizer

(This special issue belongs to the Section Molecular Oncology)

New Insight into Therapeutic Potential of Targeted Nanoparticles

edited by

Aldo Nicosia

submission deadline 28 Jun 2024 | Viewed by 421 | Submission Open

Keywords: targeted nanoparticles; theranostics; bioimaging; targeted therapy; photothermal therapy; combination therapy; controlled release; reduced side effects

(This special issue belongs to the Section Molecular Nanoscience)

Rice Molecular Breeding and Genetics: 3rd Edition

edited by

Deyong Ren

submission deadline 28 Jun 2024 | 1 articles | Viewed by 414 | Submission Open

Keywords: molecular genetics and breeding; cell biology; genetic resource innovation; gene cloning; genome editing; abiotic stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Plant-Microbe Interaction: Current Status and Future Directions

edited by

Juan Manuel Ruiz Lozano

submission deadline 28 Jun 2024 | Viewed by 358 | Submission Open

Keywords: beneficial micro-organism; climate change; crop productivity; environmental stress; food production; plant growth; stress mitigation; yield

(This special issue belongs to the Section Molecular Plant Sciences)

Metal Oxides Nanomaterials: Synthesis and Molecular Electrochemistry Applications

edited by

Carmen Lǎzǎu

and

Cornelia Bandas

submission deadline 28 Jun 2024 | Viewed by 300 | Submission Open

Keywords: inorganic binding biomolecules; nanostructured materials; metal oxide nanoparticles; metal oxide– polymeror; active surface sites

(This special issue belongs to the Section Materials Science)

Protein–Protein Interactions of Platelet Receptors

edited by Alexandre Slater

submission deadline 28 Jun 2024 | Viewed by 276 | Submission Open

Keywords: thrombosis; antiplatelet; activation; interaction; inhibition

(This special issue belongs to the Section Molecular Biology)

Zebrafish as a Model in Human Disease 3.0

edited by

Andrea Vettori

Nicola Facchinello

and

Marco G. Schiavone

submission deadline 28 Jun 2024 | Viewed by 263 | Submission Open

Keywords: zebrafish; CRISPR/Cas9; transgenic lines; biosensors; endothelial cells; extracellular matrix; genetic mutant for human disease modeling; xenografts

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Vector-Borne Diseases of Medical Interest: From Bench to Application 3.0

edited by

Denis Sereno

submission deadline 28 Jun 2024 | Viewed by 258 | Submission Open

Keywords: vector-borne infectious diseases

(This special issue belongs to the Section Molecular Microbiology)

Omics Technologies in Food Bioactives Research

edited by

Gerardo Alvarez-Rivera

submission deadline 28 Jun 2024 | Viewed by 187 | Submission Open

Keywords: food bioactivity; agri-food products; phytochemicals; health-promoting compounds; bioactive compounds; green extraction; metabolomics; lipidomics; proteomics; trascriptomics; foodomics; functional ingredients; nutraceuticals

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Anti-cancer Drugs: The Past, Present and Future

edited by

Hyeung-Jin Jang

submission deadline 28 Jun 2024 | Viewed by 130 | Submission Open

Keywords: anti-cancer; natural compound; herbal medicine; plant extract; novel biomarker; obesity; diabetes; inflammation; drug discovery; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Gene Editing for Disease Modeling and Therapeutics

edited by

Rivka Ofir

submission deadline 29 Jun 2024 | 5 articles | Viewed by 8817 | Submission Open

Keywords: gene editing methodology; CRISPR; iPSC; knockout; activation; off target; differentiation; drug discovery

(This special issue belongs to the Section Molecular Genetics and Genomics)

Coronavirus Disease (COVID-19): Pathophysiology 5.0

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 29 Jun 2024 | 2 articles | Viewed by 8118 | Submission Open

Keywords: SARS-CoV-2; coronavirus; pandemic; viral diseases; pediatrics; inflammation; immune cells; macrophages; pneumonia; vaccines; cytokines; cytokine storm; PIMS; immunity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 3rd Edition

edited by

Marianna Lauricella

and

Antonella D'Anneo

submission deadline 29 Jun 2024 | 2 articles | Viewed by 3233 | Submission Open

Keywords: obesity; adipokines; obesogens; genetic predisposition; natural/synthetic compounds; cardiovascular disorders; type II diabetes; non-alcoholic fatty liver disease; cancer

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Biology of AT-Hook Motif Containing Proteins

edited by

Manfioletti Guidalberto

Riccardo Sgarra

and

Monica Fedele

submission deadline 29 Jun 2024 | 1 articles | Viewed by 2235 | Submission Open

Keywords: AT-hook; Chromatin; DNA binding; DNA minor groove; transcription factors; architectural factors; chromatin remodeling; enhanceosome; epigenetic

(This special issue belongs to the Section Molecular Biology)

Looking into the Skin in Health and Disease: From Microscopy Imaging Techniques to Molecular Analysis (2nd Edition)

edited by

Monica Neagu

Mihaela Adriana Ilie

and

Constantin Caruntu

submission deadline 29 Jun 2024 | 2 articles | Viewed by 2230 | Submission Open

Keywords: skin imaging; molecular analysis; skin physiology; dermatopathology; skin cancer; skin inflammation; molecular biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism in Epithelial-Mesenchymal Transition (EMT) and Fibrosis: 2nd Edition

edited by

Sabrina Lisi

and

Margherita Sisto

submission deadline 29 Jun 2024 | 2 articles | Viewed by 2226 | Submission Open

Keywords: inflammation; cancer; EMT; autoimmunity; fibrosis; salivary glands

(This special issue belongs to the Section Molecular Biology)

Anaerobic Digestion Process from the Viewpoint of Chemical, Biochemical and Microbiological Aspects

edited by

Agnieszka Pilarska

submission deadline 29 Jun 2024 | 1 articles | Viewed by 1748 | Submission Open

Keywords: anaerobic digestion; biogas/methane; VFAs composition; inhibitors; biochemical pathways; enzymatic activity; biocatalysts; microbial community; syntrophic interactions; microbial carrier

(This special issue belongs to the Section Molecular Microbiology)

Natural and Synthetic Biomaterials in Biomedical Applications

edited by

Adina Musuc

submission deadline 29 Jun 2024 | 1 articles | Viewed by 722 | Submission Open

Keywords: biocompatibility; biodegradability; tissue engineering; regenerative medicine; drug delivery systems; nanostructured biomaterials; hybrid and composite biomaterials; smart biomaterials; innovative fabrication techniques

(This special issue belongs to the Section Materials Science)

Advancements in Personalized Medicine: Integrating Genomic Insights and Therapeutic Strategies

edited by

Mariarosaria Boccellino

submission deadline 29 Jun 2024 | 1 articles | Viewed by 673 | Submission Open

Keywords: personalized medicine; genomic insights; therapeutic strategies; molecular profiling; precision medicine; molecular targets; precision oncology; genomic biomarkers

(This special issue belongs to the Section Molecular Genetics and Genomics)

Medicinal Chemistry: From Drug Design to Drug Development

edited by

Chiara Brullo

and

Andrea Spallarossa

submission deadline 29 Jun 2024 | Viewed by 556 | Submission Open

Keywords: medicinal chemistry; biological targets; drug synthesis; drug discovery; pharmaceutical chemistry; structure-activity relationships

(This special issue belongs to the Section Molecular Pharmacology)

Signal Transduction and Metabolism in Vascular Biology

edited by

Isabella Russo

submission deadline 29 Jun 2024 | Viewed by 522 | Submission Open

Keywords: endothelial cells; vascular smooth muscle cells; platelets; erythrocytes; leucocytes; oxidative stress; thrombosis; atherosclerosis

(This special issue belongs to the Section Molecular Biology)

A New Era of Sustainability: Plant Biostimulants: 2nd Edition

edited by

Giuseppe Mannino

submission deadline 29 Jun 2024 | Viewed by 380 | Submission Open

Keywords: fruit quality; phytochemical profile; plant science; food science; sustainable agriculture; biostimulant; antioxidants; food security; microbial biostimulant; animal-based biostimulant; plant-based biostimulant

(This special issue belongs to the Section Molecular Plant Sciences)

New Insights into Plant Pathology and Abiotic Stress

edited by Shoupu He

submission deadline 29 Jun 2024 | Viewed by 256 | Submission Open

Keywords: plant pathology; abiotic stress; molecular mechanisms; stress resistance; signaling pathways; epigenetics; omics technologies; disease management; climate change; plant stress responses

(This special issue belongs to the Section Molecular Plant Sciences)

Emerging Roles for Serotonin in Regulating Metabolism

edited by

Giuseppe Bruschetta

and

Patrizia Licata

submission deadline 29 Jun 2024 | Viewed by 196 | Submission Open

Keywords: serotonin; cortisol; phospholipids; glycosaminoglycans; oxidative stress; veterinary anesthesia and analgesia

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

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