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Immunotherapy in Cancer

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 49

Special Issue Editor


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Guest Editor
Center for Cancer Immunology Research, Children’s National Hospital, Children’s National Research Institute, 111 Michigan Avenue NW, Washington, DC 20010, USA
Interests: cell biology; animal model; cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Immunotherapy has emerged as a revolutionary approach in cancer treatment, offering new hope for patients with various malignancies (for example, solid tumors and hematological malignancies). By harnessing the body's immune system to target and eliminate cancer cells, immunotherapy has the potential to achieve long-lasting remission and even cures in certain cases. This innovative approach represents a significant shift from traditional cancer treatments, which primarily focus on directly targeting tumors through surgery, radiation, or chemotherapy. Despite its promise, immunotherapy faces several challenges, including the variability in patient responses, the development of resistance, and the occurrence of immune-related adverse events. These challenges underscore the complexity of the immune system's interaction with cancer and highlight the need for continued research to optimize treatment strategies.

This Special Issue will explore the current landscape of immunotherapy in cancer, focusing on the mechanisms by which the immune system can be activated or suppressed in the context of cancer. It will also examine the latest advances in immunotherapeutic agents, including immune checkpoint inhibitors; CAR-T, CAR-NK, and CAR-M cell therapy; cancer vaccines; cytokine therapies; and adoptive cell therapies. Furthermore, this Special Issue will address the challenges of immunotherapy, such as identifying biomarkers for response prediction, managing resistance, and minimizing toxicity. Finally, the implications of immunotherapy for the future of cancer treatment and the potential for combination therapies will be discussed, emphasizing the need for ongoing research and innovation in this rapidly evolving field. IJMS focuses on molecular studies in biology and chemistry, with a strong emphasis on molecular biology and molecular medicine, and we particularly welcome publications on molecular-level basic research.

Dr. Nethaji Muniraj
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunotherapy
  • biomarkers
  • immune modulation
  • combination therapies
  • solid tumors
  • hematological malignancies

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Published Papers

This special issue is now open for submission.
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