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Breakthroughs in Diagnostic Prediction and Fundamental Therapeutics of Dementia and Movement Disorders, 2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 16

Special Issue Editor


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Guest Editor
Department of Biomedical Engineering, University of Houston, Houston, TX 77204-5060, USA
Interests: coronary artery disease; stent; noninvasive monitoring; nonlinear dynamics analysis; approximate entropy; 3D co-culture; glioblastoma; astrocytes; tumor microenvironment; PEGDA; addiction; cancer research; data science in medicine
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Special Issue Information

Dear Colleagues,

The increase in patients with dementia and motor dysfunction due to the global aging population is a significant social problem. No fundamental treatment for these cognitive-motor disorders has yet been developed. Therefore, understanding the etiology of aging-related disorders and exploring unique therapeutic targets to develop total therapies are urgent issues. Accordingly, comprehending the degeneration of brain function with aging is essential. To this end, it is necessary to distinguish the molecular mechanisms required to maintain neuronal homeostasis and the characteristics of pathogenic proteins. Thus, this Special Issue focuses on the pathogenic mechanism involved in the etiology of neurodegeneration, which includes Alzheimer's disease (AD), Parkinson's (PD), and dementia with Lewy bodies (DLB), demonstrating the physiological significance of the pathogenic proteins. We also focus on the disease-related biomarkers associated with the age- and disease-induced loss of neuronal homeostasis. The goal of this Special Issue is to subsequently improve our understanding of aging-related neurodegenerative disorders and to make breakthroughs in the prediction of pathogenesis and the development of fundamental treatments for these diseases.

Potential topics include, but are not limited to: Parkinson's disease (PD), Dementia with Lewy bodies (DLB), Alzheimer's disease (AD), pathogenic proteins in the above diseases, biomarkers for AD, PD, and DLB, therapeutic targets and drugs for AD, PD, and DLB, and reviews and future perspectives on the above topics.

Due to the success of the first edition of this Special Issue, we would like to add more results and new insights from recent research projects.

https://www.mdpi.com/journal/ijms/special_issues/3POPNIW1Y3

Dr. Yasemin M. Akay
Guest Editor

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Keywords

  • Parkinson's disease
  • dementia with Lewy bodies
  • Alzheimer's disease
  • pathogenic protein
  • biomarker
  • therapeutic target
  • drug

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