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Targeting Metabolic Reprogramming: From Pathogenesis to Therapeutic Strategies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 42

Special Issue Editors


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Guest Editor
Departamento Fisiologia Humana, Histologia Humana, Anatomia Patologica y Educacion Fisica y Deportiva, Facultad de Medicina, Universidad de Malaga, 29071 Malaga, Spain
Interests: myelin; oligodendrocyte; neurodegenerative disease; metabolism

E-Mail Website
Guest Editor
Departamento Fisiologia Humana, Histologia Humana, Anatomia Patologica y Educacion Fisica y Deportiva, Facultad de Medicina, Universidad de Malaga, 29071 Malaga, Spain
Interests: immunopathology; oncology; haemathology; autoinmune diseases

E-Mail Website
Guest Editor
Departamento Fisiologia Humana, Histologia Humana, Anatomia Patologica y Educacion Fisica y Deportiva, Facultad de Medicina, Universidad de Malaga, 29071 Malaga, Spain
Interests: Alzheimer’s disease; transgenic models; neuroinflammation; tauopathy
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Special Issue Information

Dear Colleagues,

Metabolic reprogramming is a hallmark of cancer cells, but it also occurs in other pathological conditions such as chronic lung diseases, rheumatoid arthritis, cardiovascular diseases, neurodegenerative diseases, and viral pathogenesis, among others.

Despite the increasing interest in this field, the molecular mechanisms underlying metabolic reprogramming in many of the above-mentioned pathologies are still scarce. Metabolic reprogramming might involve changes in glycolysis, the pentose phosphate pathway, glutaminolysis, mitochondrial metabolism, lipid metabolism, amino acid metabolism, or any other biosynthetic and bioenergetic pathways. Therefore, any natural or synthetic compound capable of modifying the activity of any of these pathways altered in the aforementioned diseases might be considered a potential therapeutic candidate to test.

This Special Issue aims to gather a broad collection of any basic and preclinical research that investigates metabolic reprogramming as a key regulator in diverse disease pathogenesis and as a novel target to decipher innovative therapeutic strategies.

Dr. Beatriz García-Díaz
Prof. Dr. Alejandro Escamilla
Prof. Dr. Raquel Sanchez-Varo
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolism
  • therapy
  • mitochondria
  • pathogenesis
  • bioenergetics

Published Papers

This special issue is now open for submission.
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