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Basic Mechanisms of Physiological and Pathological Autoimmunity and Their Role in the Development of Autoimmune Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 169

Special Issue Editor


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Guest Editor
Department of Immunology and Biotechnology, Clinical Center, Medical School, University of Pécs, Szigeti u, 12, 7643 Pécs, Hungary
Interests: immunology; autoimmunity; autoimmune diseases; immunological methods

Special Issue Information

Dear Colleagues,

We are pleased to announce the commencement of a Special Issue focusing on the significant topic of autoimmune research. Understanding the intricate relationship between physiological and pathological autoimmunity is paramount in elucidating the complexities inherent in the development of autoimmune diseases.

Over the past decades, extensive research has been conducted on physiological/natural and pathological autoimmunity, revealing the crucial role of the natural autoimmunity network in acting as a frontline defense against infections and facilitating the prompt clearance of dead cells and cell debris. Recent studies have shed light on how natural immunity contributes to the efficacy of vaccinations and aids in defending against mutated and tumorous cells. These aspects collectively form vital components of physiological immune regulation.

Simultaneously, the genetic backdrop and individual status of the physiological autoimmune network can render an organism susceptible to a targeted immune response triggered by specific environmental factors, resulting in prolonged attacks on its own structures and the eventual onset of autoimmune diseases.

We invite submissions of original articles, mini reviews, or theoretical papers for consideration in this Special Issue.

Prof. Dr. Péter Németh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • physiologic autoimmunity
  • autoimmune diseases
  • natural immune system
  • pathologic autoimmunity

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Published Papers

This special issue is now open for submission.
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