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Small Open Reading Frames Encoded by lncRNAs and Other RNAs-Significance in Cell Functions and Disease Formation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 132

Special Issue Editor


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Guest Editor
Department of Microbiology and Immunology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA
Interests: regulation of gene expression by small RNAs; functions of non-coding genomic regions; lncRNA gene origins and their evolution
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Special Issue Information

Dear Colleagues,

Over the past decade, many non-canonical small open reading frames (sORFs) have been found in diverse species and these have been shown to be translated into proteins. Many are encoded by a class of lncRNAs termed bifunctional RNAs. These RNA transcripts offer new insights in cellular functions. An example is the sORF encoded by lncRNA MIR155HG that is found to suppress autoimmune inflammation.  Bifunctional RNAs represent an emerging field of research with possibilities of discovering new cellular functions and relevance to disease processes.

We are pleased to invite researchers to contribute original research concerning sORFs encoded by lncRNA transcripts, including studies on circular RNAs, miRNAs and other RNAs. Reviews on the topic are also welcome.

Prof. Dr. Nicholas Delihas
Guest Editor

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Keywords

  • circular RNAs
  • miRNAs
  • lncRNAs
  • sORFs

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