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RNA Modifications in Response to Physical Activity: Implications for Rehabilitation and Disease Management

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 34

Special Issue Editors


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Guest Editor
Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, 40125 Bologna, Italy
Interests: role of RNA modifications in muscle adaptation and repair; gene expression and epigenetic regulation in exercise; RNA-based therapeutics for chronic disease management; personalized medicine approaches using RNA biomarkers in sports science

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Guest Editor
Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy
Interests: role of RNA modifications in muscle adaptation and repair; gene expression and epigenetic regulation in exercise; RNA-based therapeutics for chronic disease management; personalized medicine approaches using RNA biomarkers in sports science

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the critical role of RNA modifications in response to physical activity and their implications for rehabilitation. It is known that physical activity can modulate several genes, playing a specific role in various diseases, including cancer. Additionally, physical activity can also modulate non-coding RNAs, such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs). These RNA molecules regulate gene expression and influence processes such as muscle adaptation, inflammation, tissue repair, and metabolic pathways. Emerging research demonstrates that physical exercise can alter the expression of specific genes and ncRNAs, potentially enhancing muscle regeneration, reducing inflammation, and improving overall recovery following injury. This collection of studies delves into how RNA modulation through exercise can be harnessed to optimize rehabilitation protocols, enhance athletic performance, and aid in chronic disease management. By integrating molecular insights with clinical practice, this issue highlights innovative approaches to personalized medicine in rehabilitation and sports science.

Dr. Roberto Tedeschi
Dr. Francesca Gorini
Guest Editors

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Keywords

  • RNA modifications
  • non-coding RNAs (ncRNAs)
  • physical activity
  • gene expression
  • rehabilitation and disease management
  • epigenetic regulation
  • exercise-induced RNA expression
  • miRNA in inflammation control

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