Epigenetic Regulation in Human Brain 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 263
Special Issue Editor
Interests: neurobiology; epigenetics; molecular biology; DNA methylation; DNA hydroxymethylaion; neuropsychiatric disorders; flow cytometry; high-throughput sequencing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The human brain is an organ of enormous complexity, composed of a multitude of cell types, including various populations of neuronal and glial cells. Epigenetics has been recognized for a long time as a group of molecular mechanisms that are essential in establishing and maintaining this complexity. Understanding the epigenetics of brain cell types is also necessary to uncover the mechanisms underlying nervous system disorders, which often display cell type-specific aetiology. However, in recent years, a number of methodological advances have allowed us to study brain epigenetics at cell-type resolution for the first time and brought the recognition of often vast and unexpected differences between the epigenomic profiles of brain cell populations. Despite this fast and promising progress, the field is currently wide open for new insights and discoveries, especially in the studies of brain development, disease, and ageing. A significantly more thorough understanding of neuroepigenetic mechanisms is also needed before we can efficiently transfer this line of research to the stage of therapeutic opportunities. In this Special Issue, we will highlight modern developments in the field of neuroepigenetics of human brain cell populations, in its relationship to brain development, health, and disease.
Due to the success of the 1st edition, we would like to add more results and new insights from recent research projects. You can find the 1st edition at the following link: https://www.mdpi.com/journal/ijms/special_issues/Epigene_Brain
Dr. Alexey Kozlenkov
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- epigenetics
- DNA methylation
- histone modifications
- human brain
- neurons
- glutamatergic neurons
- glia
