Molecular Mechanism and Therapy of Psoriasis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 21
Special Issue Editor
Interests: psoriasis; inflammatory skin disease; cytokine; ILC3, biologics; JAK inhibitor; small molecule
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The skin is one of the largest immune organs involving innate and acquired immune systems. Thus, it can respond to exogenous stimuli, producing large amounts of proinflammatory cytokines that result in systemic inflammation.
Psoriasis is an intractable inflammatory cytokine-mediated skin disorder. Due to complications and comorbidities, including cerebro-cardiovascular complications, the average life span of people with psoriasis is 6 years shorter than that of the population without a history of psoriasis. Numerous types of biologics and small molecules have been discovered and used in routine clinical practice. They have proven to be remarkably effective and have improved patients’ quality of life. However, there are still many unanswered questions regarding the pathogenesis of the disease, and further discoveries of new cytokines and mediators are expected.
For this Special Issue, we welcome clinical evidence and research findings focusing on molecular mechanisms and therapy in psoriasis.
Prof. Dr. Keiichi Yamanaka
Guest Editor
Manuscript Submission Information
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Keywords
- psoriasis
- inflammatory skin disease
- cytokine
- innate lymphoid cell
- systemic inflammation
- JAK inhibitor
- small molecule
