Innovative Approaches to Enhancing Bioavailability and Bioaccessibility of Bioactive Compounds from Plant and Food Extracts
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 229
Special Issue Editor
Interests: pharmacy; natural products research; bioactive compounds; antioxidant activity; deep eutectic solvents; modern extraction techniques; optimization of extraction of bioactive compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, there has been a growing interest in plant extracts, nutraceuticals, and functional foods due to their potential health benefits and role in preventing and managing chronic diseases. Understanding the mechanisms by which these natural compounds exert their beneficial effects is critical to uncover their full potential. As research continues to explore the complex interactions between bioactive compounds and biological systems, innovative approaches are needed to enhance their bioavailability and bioaccessibility, thereby maximizing their efficacy.
As the Guest Editor of this special issue, I invite contributions which aim to present innovative studies that enhance the health benefits of bioactive compounds by employing novel approaches and investigating molecular mechanisms.
This Special Issue could explore a range of important topics, including but not limited to:
- Investigate how nanotechnology, liposomes, or other delivery systems can improve the bioavailability of bioactive compounds.
- Examine how combinations of plant and food extracts can enhance the bioaccessibility and bioavailability of bioactive compounds. Studies investigating molecular synergy between different compounds, including their interactions and their combined effects on biological pathways are welcome.
- Discuss the latest molecular models for assessing bioavailability and bioaccessibility, including in vitro assays and preclinical models that incorporate biomolecular experiments. Submissions that include clinical or model-based research with a strong emphasis on molecular biology and molecular mechanisms are welcome.
- Explore how the food matrix and different processing methods influence the stability, bioavailability, and bioaccessibility of bioactive compounds.
- Understand how bioactive compounds are absorbed, transported, and metabolized in the body and how these processes affect their bioavailability and efficacy. This Special Issue will provide insights into the molecular pathways and mechanisms through which these compounds exert their effects, contributing to a deeper understanding of their potential therapeutic benefits.
- The use of molecular techniques such as proteomics, genomics, and metabolomics to identify biomarkers and pathways that are influenced by bioactive compounds, thus allowing the development of more targeted and effective formulations. Understanding these molecular interactions will significantly contribute to translating laboratory results into practical applications that can improve human health through diet and nutrition.
Researchers and scholars are welcomed to submit their original research articles, comprehensive reviews, and short communications that align with the themes of this special issue intended to provide a unique platform for advancing the collective understanding of bioactive compounds and their vital role in promoting health.
Dr. Ana-Maria Vlase
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioactive compounds
- nutraceuticals
- functional foods
- in vitro and in vivo models
- bioavailability
- bioaccessibility
- nanotechnology
- delivery systems
- molecular mechanisms
- proteomics
- genomics
- metabolomics
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