Exploring the Therapeutic Potential of Modulators of Regulated Cell Death for Retinal Atrophy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 January 2025 | Viewed by 316
Special Issue Editor
Special Issue Information
Dear Colleagues,
For over 50 years, various forms of regulated cell death (RCD), both apoptotic and non-apoptotic, have been identified and implicated in the progression of retinal degeneration. These RCD mechanisms, involving tightly controlled signaling cascades, offer potential targets to halt degeneration without disturbing retina physiology. However, no approved anti-RCD interventions have yet fulfilled this expectation. This Special Issue aims to provide a comprehensive overview of RCDs involved in Dry Age-Related Macular Degeneration (AMD) and Inherited Retinal Disorders (IRDs*). We invite authors to submit original research and review articles exploring RCD in retinal atrophy. Our target audience includes researchers and clinicians who are actively involved in or interested in retinal degeneration. Lastly, we aim to address the remaining challenges in developing effective treatments based on the inhibition of individual or combined RCD mechanisms. By publishing in this Special Issue, authors will benefit from the journal’s high visibility and reputation in the field. Please refer to the submission guidelines on the journal’s website for more information about the submission process and deadlines.
*IRDs include, but are not limited to, Stargardt Disease (STGD), Leber Congenital Amaurosis (LCA), X-linked Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CRD), and Choroideremia.
Dr. Marcelo Nociari
Guest Editor
Manuscript Submission Information
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Keywords
- Stargardt disease
- dry-age related macular degeneration
- cell death
- atrophy
- regulated necrosis
- apoptosis
- autophagy
- proteostasis
- lipofuscin
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