Molecular Mechanisms: New Insights into the Pathogenesis of Neonatal Disorders
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 116
Special Issue Editor
Interests: neonatal sepsis; SARS-CoV-2; infectious diseases; neonatal sepsis diagnosis decision-making; inflammatory biomarkers; congenital infections; neonatal sepsis-associated coagulopathy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neonatology, emerging as a field over the past 50 years, has seen rapid technological progress and significant advances in perinatal treatment and neonatal intensive care. These developments have notably improved survival rates following premature birth, especially for infants born at extremely low gestations (<28 weeks). Concurrently, the limits of viability have progressively decreased to as early as 22–24 weeks of gestation in many countries.
Despite these strides in perinatal care, neonatal morbidity rates and severe long-term impairments remain substantial among extremely preterm neonates. Recent innovations in neonatology have indeed bolstered survival rates for newborns, particularly those born extremely premature. Technological advancements and sophisticated medical practices have greatly enhanced hospitals’ capabilities to deliver effective care, thereby augmenting the chances of survival for these vulnerable infants. Nonetheless, morbidity rates persist at concerning levels, with premature infants frequently encountering critical health challenges such as respiratory complications, neurodevelopmental disorders, and sensory impairments necessitating prolonged medical intervention and monitoring.
A deeper comprehension of these challenges relies heavily on understanding molecular mechanisms. In recent decades, there has been a notable shift from merely identifying the causative factors of diseases to delving into molecular pathogenesis. This specialized field focuses on unraveling the molecular changes triggered by environmental factors and other influences that lead to the development of various pathologies. By exploring molecular pathogenesis in depth, we can uncover the intricate pathways implicated in neonatal disease, whether through mechanisms involving loss or gain of function. This understanding of the specific roles played by genes, proteins, and pathways allows for the development of precisely targeted therapies tailored to address particular diseases. The continuous expansion of our knowledge about disease mechanisms has opened new avenues for innovative approaches to neonatal care and management.
Therefore, this Special Issue aims to gather high-quality original research and reviews focusing on an innovative and broad perspective in the field of current understanding of the molecular pathogenesis of neonatal morbidities. It specifically highlights the inflammatory, immune, infectious, and genetic mechanisms underlying disease development.
Dr. Rozeta Sokou
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neonate
- neonatal infections
- molecular and cellular mechanisms
- necrotizing enterocolitis
- immature immune system
- neonatal inflammation
- epigenetic modification
- regulatory RNAs
- bronchopulmonary dysplasia
- neonatal hypoxic–ischemic injury
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
