The Molecular Role of Platelets in Human Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 42
Special Issue Editors
2. Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA
Interests: emergency medicine; critical care; anesthesiology; research outcomes; epidemiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Platelets are vital for maintaining the integrity of blood vessel walls as they regulate bleeding and the formation of blood clots. Secretory platelets discharge substances from storage granules, biomediators, and membrane vesicles. This release impacts both typical and atypical pathophysiological mechanisms. Platelets, however, assimilate plasma and cellular components, thereby impacting their ability to respond. Examining platelet function and identifying the cells and molecules that regulate their activation and aggregation in blood vessels is crucial for understanding the protective or damaging impact of platelets on organisms. Recent advances in the study of platelet biology have uncovered the role of platelets in the development of different diseases, going beyond just blood clotting disorders. Platelets have a dual function as both agents and recipients in the development of diseases. This offers a favorable prospect for clinical applications that enable the detection and quantification of distinct platelet components as innovative biomarkers and targets for therapeutic interventions in various pathological conditions.
In this Special Issue of the International Journal of Molecular Sciences, entitled "The Molecular Role of Platelets in Human Diseases", we strongly encourage authors to submit original articles and reviews that are relevant to, but not restricted to, the following subjects:
- Platelets as novel biomarkers and targets for human diseases;
- The relationship between platelets and cardiovascular disease, cancer, obesity, infection, neurodegeneration, and other diseases;
- Innovative treatment approaches for diseases related to platelets.
Prof. Dr. Lukasz Szarpak
Dr. Michał Pruc
Guest Editors
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Keywords
- platelet
- biomarkers
- platelet membrane proteins
- platelet-derived microparticles
- platelet-related diseases
- thrombosis
- inflammatory diseases
- cardiovascular disease
- cancer
- tumor growth and metastasis
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