Gender Related Molecular Mechanisms in Neurological Disorders
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 353
Special Issue Editor
Interests: neurological disorders; neuroepidemiology; multiple scleorsis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Sex differences represent key issues in understanding clues of pathological mechanisms in neurological diseases. A relevant amount of studies have been performed in the past with the aim of investigating how molecular differences related to sex dependent aspects could shed some light to better understand aetiology and pathological mechanisms of neurological diseases. Sex differences have been reported for instance in several molecular and biochemical pathways (like oxidative stress). Oxidative stress mechanisms are reported to be higher in men than in women. Hormonal aspects have been usually considered the major drivers of sex differences in neurolgical diseases but, more recently, other pathways such as post genomic or epigenomic modification seem to give a considerable contribution.
The purpose of this Special Issue of IJMS is to explore how sex and gender issues may act in influencing molecular pathways of neurological disorders and of neurodegeneration, in order to understand clues about the pathology underlying neurodegenerative processes. This Special Issue will provide an opportunity to cover studies considering animal models, biochemical and/or experimental studies investigating molecular pathways, or reviews exploring molecular and pathogenic mechanisms revealing new insights into the comprehension of the pathophysiological modification associated with the effects of sex and gender on neurological diseases. The issue will contribute to highlight how pathologic processes of neurological and neurodegenerative diseases can be determined or modified by sex dependent issues.
Dr. Paolo Ragonese
Guest Editor
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Keywords
- gender and sex differences
- neurological disorders
- neurodegeneration
- neuroprotection
- Parkinson’s disease
- stroke
- multiple sclerosis
- dementia
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