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24 April 2025
World Malaria Day—“Malaria Ends with Us: Reinvest, Reimagine, Reignite”, 25 April 2025


World Malaria Day, observed annually on 25 April, is a global reminder of the urgent need to stay focused on the fight against malaria—a preventable and treatable disease that still threatens millions of lives, especially in vulnerable communities. Despite considerable progress over the past two decades, malaria continues to take a heavy toll, particularly in sub-Saharan Africa, where children under five remain at most risk.

The theme for 2025, “Malaria Ends with Us: Reinvest, Reimagine, Reignite”, is a powerful call to action. It is a strong reminder that the fight against malaria is not over, and that the power to end it lies with all of us.

In recognition of this vital cause, MDPI is spotlighting impactful research across a selection of its journals, highlighting contributions that advance the understanding, prevention, and treatment of malaria. Featured journals include Cells, Insects, Journal of Clinical Medicine (JCM), Metabolites, Parasitologia, Pathogens, Pharmaceuticals, Reports, and TropicalMed. By bringing these articles to the forefront, MDPI reaffirms its commitment to open access knowledge and global health equity.

 


Prof. Tu Youyou was awarded the Nobel Prize in Physiology or Medicine in 2015 for discovering artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from malaria.

To honor Prof. Tu Youyou’s remarkable contributions and to continue with her achievements, MDPI established the Tu Youyou Award in 2016. This award aims to acknowledge exceptional scholars committed to the research fields of natural products chemistry and medicinal chemistry.

The winners of the 2024 Tu Youyou Award will be announced on 30 April. Visit the award website for the latest updates!

 

 

Blood Source and Anesthetics Effects on the Maintenance of Anopheles darlingi in the Lab-Rearing Condition
by José Daniel Costa Pontual, Natália Vitória Coelho, Najara Akira Costa dos Santos, Alessandra da Silva Bastos, Jéssica Evangelista Araújo, Alice Oliveira Andrade, Jansen Fernandes Medeiros and Maisa da Silva Araujo
Insects 2025, 16(3), 281; https://doi.org/10.3390/insects16030281

Identification of Bioactive Metabolites of Capirona macrophylla by Metabolomic Analysis, Molecular Docking, and In Vitro Antiparasitic Assays
by Joseph Evaristo, Elise de Laia, Bruna Tavares, Esdras Mendonça, Larissa Grisostenes, Caroline Rodrigues, Welington do Nascimento, Carolina Garcia, Sheila Guterres, Fábio Nogueira et al.
Metabolites 2025, 15(3), 157; https://doi.org/10.3390/metabo15030157

Duplication of a Type-P5B-ATPase in Laverania and Avian Malaria Parasites and Implications About the Evolution of Plasmodium
by Mark F. Wiser
Parasitologia 2025, 5(1), 6; https://doi.org/10.3390/parasitologia5010006

Effect of Health Education Intervention on Knowledge and Adherence to Intermittent Preventive Treatment of Malaria in Pregnancy Among Women
by Pauline N. Atser, Gommaa Hayat and Uchenna B. Okafor
Healthcare 2025, 13(2), 105; https://doi.org/10.3390/healthcare13020105

Uncovering the Mechanism of Action of Antiprotozoal Agents: A Survey on Photoaffinity Labeling Strategy
by Alessandro Giraudo, Cristiano Bolchi, Marco Pallavicini, Roberto Di Santo, Roberta Costi and Francesco Saccoliti
Pharmaceuticals 2025, 18(1), 28; https://doi.org/10.3390/ph18010028

Contribution of Magnetic Resonance Imaging Studies to the Understanding of Cerebral Malaria Pathogenesis
by Alicia Comino Garcia-Munoz, Isabelle Varlet, Georges Emile Grau, Teodora-Adriana Perles-Barbacaru and Angèle Viola
Pathogens 2024, 13(12), 1042; https://doi.org/10.3390/pathogens13121042

Prophylaxis Failure and Successful Management of Delayed-Onset Malaria with Renal Complications: A Case Report with Oral Artemether-Lumefantrine Treatment
by Ilir Tolaj, Gramoz Bunjaku, Murat Mehmeti and Yllka Begolli
Reports 2023, 6(4), 53; https://doi.org/10.3390/reports6040053

Sensitivity Assessment of a Multiplex and Real-Time PCR Protocols for the Detection of Malaria in External Quality Control Samples in the Malaria Reference Center in Greece
by Nikolaos Tegos, Christos Goumenopoulos, Anastasia Mpimpa, Vasilios Papavasilopoulos, Stavroula Beleri and Eleni Patsoula
Parasitologia 2024, 4(2), 150-161; https://doi.org/10.3390/parasitologia4020013

Prevention of Malaria in Pregnant Women and Its Effects on Maternal and Child Health, the Case of Centre Hospitalier de Kingasani II in the Democratic Republic of the Congo
by Japhet Kabalu Tshiongo, Trésor Zola Matuvanga, Patrick Mitashi, Vivi Maketa, Henk D. F. H. Schallig, Petra F. Mens, Hypolite Muhindo Mavoko and Junior Matangila Rika
Trop. Med. Infect. Dis. 2024, 9(5), 92; https://doi.org/10.3390/tropicalmed9050092

An Epidemiological Survey of Malaria Infection in Espírito Santo State, Brazil, from 2007 to 2017
by Nayna Carvalho Oliveira, Lais Rosa Boscalha, Cinthia Emerich Toledo, Felipe Sarlo Pezzin, Bruno Costanza Cisari, Suellen Rodrigues Maran, Laís Rodrigues Diniz, Pedro Henrique Schultz Corcino Freitas, Adenilton Cruzeiro, Frederico Eutropio et al.
Parasitologia 2023, 3(3), 215-222; https://doi.org/10.3390/parasitologia3030022

Low Prevalence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions—A Multiregional Study in Central and West Africa
by Tina Krueger, Moses Ikegbunam, Abel Lissom, Thaisa Lucas Sandri, Jacques Dollon Mbama Ntabi, Jean Claude Djontu, Marcel Tapsou Baina, Roméo Aimé Laclong Lontchi, Moustapha Maloum, Givina Zang Ella et al.
Pathogens 2023, 12(3), 455; https://doi.org/10.3390/pathogens12030455

Impact of the COVID-19 Pandemic on Malaria Control in Africa: A Preliminary Analysis
by Liping Gao, Qi Shi, Zhiguo Liu, Zhenjun Li and Xiaoping Dong
Trop. Med. Infect. Dis. 2023, 8(1), 67; https://doi.org/10.3390/tropicalmed8010067

Control and Surveillance of Mosquitoes to Reduce the Spread of Mosquito-Borne Disease

“Molecular and Cellular Research on Targets for Antimalarial Therapy Development”

“One Health Approach to Malaria Elimination

Recent Advancements in the Development of Antiprotozoal Agents

Dysbiosis and Metabolic Disorders of the Microbiota

 

24 April 2025
World Immunization Week—“Immunization for All is Humanly Possible”, 24–30 April 2025


World Immunization Week, celebrated annually during the last week of April, is a global health awareness initiative highlighting the critical role of vaccines in protecting people of all ages against vaccine-preventable diseases.

On this momentous occasion, we are thrilled to present a thoughtfully selected compilation of articles and Special Issues that focus on the pioneering research and cutting-edge strategies in immunology and vaccination. We encourage readers to delve into these scholarly contributions and stand with us in our commitment to preserving and enhancing global immunization health.

Join us as we explore the latest findings and innovative methods that are shaping the future of immunization. Together, we can strive towards a world where every individual has access to the life-saving benefits of vaccines.

We hope that the established journals in the fields of biology life sciences and medicine and pharmacology at MDPI will provide a communication platform for innovative ideas regarding prevention and treatment.

Biology & Life Sciences

Medicine & Pharmacology

 

Engineering

Lifestyle and Biochemical Parameters That May Hamper Immune Responses in Pediatric Patients After Immunization with the BNT162b2 mRNA COVID-19 Vaccine
by Anthie Damianaki, Antonios Marmarinos, Margaritis Avgeris, Dimitrios Gourgiotis, Elpis-Athina Vlachopapadopoulou, Marietta Charakida, Maria Tsolia and Lydia Kossiva
Diseases 202513(3), 78; https://doi.org/10.3390/diseases13030078

Evaluating the Potential of Herbal Extracts as Treatment in Immune Thrombocytopenia: A Review of Evidence and Limitations
by Russell W. Wiggins, Jihoo Woo, John Nicholas Cauba and Shizue Mito
Appl. Biosci. 20254(1), 1; https://doi.org/10.3390/applbiosci4010001

Immunotherapeutic Strategies for the Treatment of Glioblastoma: Current Challenges and Future Perspectives
by Ilaria Salvato and Antonio Marchini
Cancers 202416(7), 1276; https://doi.org/10.3390/cancers16071276

Unveiling Extramedullary Hematopoiesis: A Case Report Highlighting the Causes, Symptoms, and Management Strategies
by Konstantinos Manganas, Aikaterini Xydaki, Angeliki Kotsiafti, Olympia Papakonstantinou and Sophia Delicou
Thalass. Rep. 202414(2), 26-32; https://doi.org/10.3390/thalassrep14020004

Inhibitors of Immune Checkpoints: Small Molecule- and Peptide-Based Approaches
by Natalie Fuchs, Longfei Zhang, Laura Calvo-Barreiro, Katarzyna Kuncewicz and Moustafa Gabr
J. Pers. Med. 202414(1), 68; https://doi.org/10.3390/jpm14010068

Vaccine-Induced Immune Thrombotic Thrombocytopenia: Clinicopathologic Features and New Perspectives on Anti-PF4 Antibody-Mediated Disorders
by Yi Zhang, Anna-Lise Bissola, Jared Treverton, Michael Hack, Mark Lychacz, Sarah Kwok, Addi Arnold and Ishac Nazy
J. Clin. Med. 202413(4), 1012; https://doi.org/10.3390/jcm13041012

Immune Response to Respiratory Viral Infections
by Antonella Gambadauro, Francesca Galletta, Alessandra Li Pomi, Sara Manti and Giovanni Piedimonte
Int. J. Mol. Sci. 202425(11), 6178; https://doi.org/10.3390/ijms25116178

Neutrophil Extracellular DNA Traps in Response to Infection or Inflammation, and the Roles of Platelet Interactions
by William A. Chen and Danilo S. Boskovic
Int. J. Mol. Sci. 202425(5), 3025; https://doi.org/10.3390/ijms25053025

Host Immune Regulation in Implant-Associated Infection (IAI): What Does the Current Evidence Provide Us to Prevent or Treat IAI?
by Zulipikaer Maimaiti, Zhuo Li, Chi Xu, Jun Fu, Li-Bo Hao, Ji-Ying Chen and Wei Chai
Bioengineering 202310(3), 356; https://doi.org/10.3390/bioengineering10030356

Airborne Pollen Calendar of Toluca City, Mexico
by Maria Cid del Prado, Osvaldo Zarco-Cid del Prado, Hilda Adriana Guerrero-Parra and Karla Elisa Juárez Contreras
Aerobiology 20231(1), 54-69; https://doi.org/10.3390/aerobiology1010005

Innovative Therapies and Management of Complications in Hemoglobinopathies Peptide-Based Vaccines: An Efficient Alternative to Combat Infectious Diseases and Drug Resistance
Immunotherapy in the Management of Hematologic Malignancy Feature Review for Applied Biosciences
Advances in Transfusion Medicine and Immunological Research Advancements in Artificial Intelligence for Bioaerosol Detection, Characterization, and Modeling

18 April 2025
Journal of Clinical Medicine | New Section “Geriatric Medicine” Established


Journal of Clinical Medicine (JCM, ISSN: 2077-0383) is an international, peer-reviewed, and open access journal on clinical and pre-clinical research. Under the guidance of the Section Editor-in-Chief, Dr. Huiberdina Lena Koek, we have established a new Section: “Geriatric Medicine”.

A message from the Section Editor-in-Chief. Dr. Huiberdina Lena Koek:
It is with pleasure that we introduce a new Section named “Geriatric Medicine”. The target articles are manuscripts with a focus on diagnostics, therapeutics, and prognostication in geriatric patients. This Section will focus on papers presenting innovative results that improve medical care for older people. This Section will publish original and review articles within the field of geriatric medicine. We hope that we will attract manuscripts on geriatric medicine of the best scientific quality.

I would like to thank all contributors for supporting our journal, which is currently thriving and expected to have an ever-increasing impact on the scientific community. I would also like to thank the editors and the Editorial Office for their excellent work in strengthening our journal’s handling of manuscripts, as well as their tireless work to increase our journal’s visibility and impact. Together, we endeavor to increase evidence-based, innovative knowledge of clinical medicine for the scientific and medical community.

Section Information:
Geriatric medicine is a crucial branch of clinical medicine that focuses on the etiology, diagnosis, treatment, and prognosis of health conditions affecting older adults. As the global population ages, the demand for specialized clinical care for the elderly continues to grow. The “Geriatric Medicine” Section of the Journal of Clinical Medicine will provide a platform for clinical research focused on the medical care and clinical management of elderly patients. This Section will cover both general geriatric care as well as specialized treatments for age-related diseases and chronic conditions commonly seen in older adults.

Subject areas (including but not limited to those below):

  • Age-related diseases;
  • Chronic disease management in the elderly;
  • Clinical geriatric pharmacology;
  • Geriatric psychiatry;
  • Geriatric neurology;
  • Frailty and mobility;
  • Rehabilitation and physical therapy in aging populations;
  • End-of-life care and palliative medicine in the elderly;
  • Nutrition and aging in the elderly;
  • Acute care for the elderly;
  • Preventive care and screening for older adults;
  • Geriatric oncology;
  • Surgery in the elderly;
  • Cardiology in the elderly;
  • Nephrology in the elderly;
  • Orthopedics in the elderly;
  • Infectious diseases in the elderly;
  • Pulmonary diseases in the elderly;
  • Endocrinology in the elderly;
  • Gastroenterology in the elderly;
  • Urogenital diseases in the elderly.

Please find more details at https://www.mdpi.com/journal/jcm/sections/geriatric_medicine.

The “Geriatric Medicine” Section is currently recruiting Guest Editors for Special Issues, which provide a platform for collaborative research on innovative geriatric medicine topics; relevant information can be found at https://www.mdpi.com/special_issues_guidelines. We are actively looking for scholars in this field to join the peer review and editorial procedures as volunteer reviewers. We provide reviewer benefits; for further details, kindly visit https://www.mdpi.com/reviewers#5_Volunteer_Reviewers.

If you are interested in the latest publications in geriatric medicine, please visit https://www.mdpi.com/search?journal=jcm&section=2634.

17 April 2025
World Hemophilia Day—“Access for All: Women and Girls Bleed Too”, 17 April 2025


On 17 April 2025, the global bleeding disorders community will come together to celebrate World Hemophilia Day. This year’s theme is “Access for all: Women and girls bleed too”.

Currently, women and girls with bleeding disorders (WGBDs) are still underdiagnosed and underserved. The global bleeding disorders community has the power—and the responsibility—to change this. Through recognition, diagnosis, treatment, and care, the quality of life of women and girls will improve, strengthening the community as a whole.

We would like to recommend some related articles, Special Issues, and MDPI journals as suitable communication platforms and believe that sharing research like this can help raise awareness of Hemophilia Day.

Managing Surgical Risks in Hemophilic Elbow Arthropathy: An In-Depth Case Study and Literature Review
by Gianluigi Pasta, Salvatore Annunziata, Roberta Ruggieri, Dario Abruzzi, Paolo Arrigoni, Eugenio Jannelli, Francesco Benazzo, Luisella Pedrotti, Erika Maria Viola, Emérito Carlos Rodriguez-Merchan and Mario Mosconi
Healthcare 2024, 12(17), 1776; https://doi.org/10.3390/healthcare12171776

Better Communication for Better Management of Persons with Hemophilia: Results from a Patients’-Clinicians’ Project to Address the New Therapeutic Landscape
by Laura Banov, Silvia Linari, Luigi Ambroso, Enrico Ferri Grazzi, Samanta Gallo, Patrizio Pasqualetti and Maria Elisa Mancuso
J. Clin. Med. 2024, 13(2), 568; https://doi.org/10.3390/jcm13020568

Six-Year, Real-World Use of Prophylaxis with Recombinant Factor IX–Albumin Fusion Protein (rIX-FP) in Persons with Hemophilia B: A Single-Center Retrospective–Prospective Study
by Antonio Coppola, Gianna Franca Rivolta, Gabriele Quintavalle, Annalisa Matichecchia, Federica Riccardi, Rossana Rossi, Anna Benegiamo, Paola Ranalli, Valeria Coluccio and Annarita Tagliaferri
J. Clin. Med. 2024, 13(5), 1518; https://doi.org/10.3390/jcm13051518

Thalassemia: Pathophysiology, Diagnosis, and Advances in Treatment
by Idris Zubairu Sadiq, Fatima Sadiq Abubakar, Hauwa Salisu Usman, Aliyu Dantani Abdullahi, Bashiru Ibrahim, Babangida Sanusi Kastayal, Maryam Ibrahim and Hassan Aliyu Hassan
Thalass. Rep. 2024, 14(4), 81-102; https://doi.org/10.3390/thalassrep14040010

Haemophilia A: A Review of Clinical Manifestations, Treatment, Mutations, and the Development of Inhibitors
by Sarmiento Doncel, Samuel, Gina Alejandra Díaz Mosquera, Javier Mauricio Cortes, Carol Agudelo Rico, Francisco Javier Meza Cadavid and Ronald Guillermo Peláez
Hematol. Rep. 2023, 15(1), 130-150; https://doi.org/10.3390/hematolrep15010014

Ultrasound Evaluation of Tendinopathy in Hemophiliac Patients for the Purpose of Rehabilitation Indications
by Danilo Donati, Paolo Spinnato, Lelia Valdrè, Lydia Piscitelli, Giuseppina Mariagrazia Farella, Enrico Pagliarulo and Maria Grazia Benedetti
J. Clin. Med. 2023, 12(13), 4513; https://doi.org/10.3390/jcm12134513

Safe and Successful Surgical Outcome in Persons with Hemophilia A with and without Inhibitors Treated with Emicizumab: A Large, Single Center, Real-World Experience
by Giancarlo Castaman, Silvia Linari, Lisa Pieri, Christian Carulli, Paolo Prosperi, Paolo Tonelli, Francesco Demartis, Rajmonda Fjerza, Monica Attanasio, Mirella Coppo and Francesca Salvianti
J. Clin. Med. 2023, 12(6), 2317; https://doi.org/10.3390/jcm12062317

A Retrospective Analysis of the American Thrombosis and Hemostasis Network Dataset Describing Outcomes of Dental Extractions in Persons with Hemophilia
by Heather Messenger, Roshni Kulkarni, Michael Recht and Chunla He
J. Clin. Med. 2023, 12(5), 1839; https://doi.org/10.3390/jcm12051839

Laboratory Rat Thrombi Lose One-Third of Their Stiffness When Exposed to Large Oscillating Shear Stress Amplitudes: Contrasting Behavior to Human Clots
by Ursula Windberger, Veronika Glanz and Leon Ploszczanski
Int. J. Transl. Med. 2022, 2(3), 332-344; https://doi.org/10.3390/ijtm2030026

Innovative Therapies and Management of Complications in Hemoglobinopathies Hematopathology: Rare Hematological Diseases

Hemophilia: Current Trends and Future Directions Patient Experience and the Quality of Health Care

10 April 2025
Journal of Clinical Medicine | Highly Cited Papers and Hot Topic Special Issues on Artificial Intelligence

As artificial intelligence (AI) technology advances at a rapid pace, clinical researchers are vigorously delving into diverse AI applications within clinical medicine. Their ultimate aim is to bring greater benefits to patients and chart new courses for the medical field.

We invite you to read the highly cited papers on artificial intelligence published in the Journal of Clinical Medicine (JCM, ISSN: 2077-0383). These papers present the latest insights and findings, and we trust they will infuse fresh inspiration and innovative thinking into your new research endeavors. Furthermore, several Special Issues centered around this topic are currently open for submissions.

1. “Face the Future—Artificial Intelligence in Oral and Maxillofacial Surgery”
by Maximilian F. Miragall, Samuel Knoedler, Martin Kauke-Navarro, Rakan Saadoun, Alex Grabenhorst, Florian D. Grill, Lucas M. Ritschl, Andreas M. Fichter, Ali-Farid Safi and Leonard Knoedler
J. Clin. Med. 2023, 12(21), 6843; https://doi.org/10.3390/jcm12216843
Full text available online: https://www.mdpi.com/2077-0383/12/21/6843

2. “Evolving the Era of 5D Ultrasound? A Systematic Literature Review on the Applications for Artificial Intelligence Ultrasound Imaging in Obstetrics and Gynecology”
by Elena Jost, Philipp Kosian, Jorge Jimenez Cruz, Shadi Albarqouni, Ulrich Gembruch, Brigitte Strizek and Florian Recker
J. Clin. Med. 2023, 12(21), 6833; https://doi.org/10.3390/jcm12216833
Full text available online: https://www.mdpi.com/2077-0383/12/21/6833

3. “Artificial Intelligence and Machine Learning in the Diagnosis and Management of Stroke: A Narrative Review of United States Food and Drug Administration-Approved Technologies”
by Anirudha S. Chandrabhatla, Elyse A. Kuo, Jennifer D. Sokolowski, Ryan T. Kellogg, Min Park and Panagiotis Mastorakos
J. Clin. Med. 2023, 12(11), 3755; https://doi.org/10.3390/jcm12113755
Full text available online: https://www.mdpi.com/2077-0383/12/11/3755

4. “Using Generative Artificial Intelligence Tools in Cosmetic Surgery: A Study on Rhinoplasty, Facelifts, and Blepharoplasty Procedures”
by Bryan Lim, Ishith Seth, Skyler Kah, Foti Sofiadellis, Richard J. Ross, Warren M. Rozen and Roberto Cuomo
J. Clin. Med. 2023, 12(20), 6524; https://doi.org/10.3390/jcm12206524
Full text available online: https://www.mdpi.com/2077-0383/12/20/6524

5. “Revolutionizing Spinal Care: Current Applications and Future Directions of Artificial Intelligence and Machine Learning”
by Mitsuru Yagi, Kento Yamanouchi, Naruhito Fujita, Haruki Funao and Shigeto Ebata
J. Clin. Med. 2023, 12(13), 4188; https://doi.org/10.3390/jcm12134188
Full text available online: https://www.mdpi.com/2077-0383/12/13/4188

6. “Using Artificial Intelligence to Predict Mechanical Ventilation Weaning Success in Patients with Respiratory Failure, Including Those with Acute Respiratory Distress Syndrome”
by Tamar Stivi, Dan Padawer, Noor Dirini, Akiva Nachshon, Baruch M. Batzofin and Stephane Ledot
J. Clin. Med. 2024, 13(5), 1505; https://doi.org/10.3390/jcm13051505
Full text available online: https://www.mdpi.com/2077-0383/13/5/1505

7. “Artificial Intelligence (AI) versus POCUS Expert: A Validation Study of Three Automatic AI-Based, Real-Time, Hemodynamic Echocardiographic Assessment Tools”
by Eyal Gohar, Amit Herling, Mor Mazuz, Gal Tsaban, Tomer Gat, Sergio Kobal and Lior Fuchs
J. Clin. Med. 2023, 12(4), 1352; https://doi.org/10.3390/jcm12041352
Full text available online: https://www.mdpi.com/2077-0383/12/4/1352

8. “Development of Bleeding Artificial Intelligence Detector (BLAIR) System for Robotic Radical Prostatectomy”
by Enrico Checcucci, Pietro Piazzolla, Giorgia Marullo, Chiara Innocente, Federico Salerno, Luca Ulrich, Sandro Moos, Alberto Quarà, Gabriele Volpi, Daniele Amparore et al.
J. Clin. Med. 2023, 12(23), 7355; https://doi.org/10.3390/jcm12237355
Full text available online: https://www.mdpi.com/2077-0383/12/23/7355

9. “An Artificial Intelligence-Enabled ECG Algorithm for Predicting the Risk of Recurrence in Patients with Paroxysmal Atrial Fibrillation after Catheter Ablation”
by Junrong Jiang, Hai Deng, Hongtao Liao, Xianhong Fang, Xianzhang Zhan, Wei Wei, Shulin Wu and Yumei Xue
J. Clin. Med. 2023, 12(5), 1933; https://doi.org/10.3390/jcm12051933
Full text available online: https://www.mdpi.com/2077-0383/12/5/1933

Special Issues:

Artificial Intelligence (AI)-Based Diagnosis in Clinical Practice
Guest Editor: Dr. Takao Fujisawa
Submission deadline: 24 July 2025

Machine Learning and Artificial Intelligence in Neurosurgery
Guest Editors: Dr. Jan Oliver Neumann and Dr. Paul Naser
Submission deadline: 31 July 2025

Surgical Precision: The Impact of AI and Robotics in General Surgery
Guest Editor: Dr. Tamara M. H. Gall
Submission deadline: 25 August 2025

Artificial Intelligence and Eye Disease
Guest Editors: Prof. Dr. Andrzej Grzybowski, Dr. Louis Arnould and Prof. Dr. Haoyu Chen
Submission deadline: 30 September 2025

4 April 2025
Journal of Clinical Medicine | Highly Cited Papers in 2024 and Hot Topic Special Issues in the Section “Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine”


We are delighted to share some highly cited papers that were published in the Section “Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine” of the Journal of Clinical Medicine (JCM, ISSN: 2077-0383) in 2024. In addition, some Special Issues in this topic are currently open for submission. The following is a list of articles and Special Issues that we believe will interest you:

1. “Reduction of Post-Surgical Facial Edema Following Bromelain and Coumarin Intake in Traumatology: A Prospective Study with 100 Patients”
by Giuseppe Consorti, Gabriele Monarchi, Mariagrazia Paglianiti, Enrico Betti and Paolo Balercia
J. Clin. Med. 2024, 13(4), 922; https://doi.org/10.3390/jcm13040922
Full text available online: https://www.mdpi.com/2077-0383/13/4/922

2. “Prevention of Breast Cancer-Related Lymphedema: An Up-to-Date Systematic Review of Different Surgical Approaches”
by Domenico Pagliara, Federica Grieco, Silvia Rampazzo, Nicola Pili, Pietro Luciano Serra, Roberto Cuomo and Corrado Rubino
J. Clin. Med. 2024, 13(2), 555; https://doi.org/10.3390/jcm13020555
Full text available online: https://www.mdpi.com/2077-0383/13/2/555

3. “Needle-Free Jet Injection of Poly-(Lactic Acid) for Atrophic Acne Scars: Literature Review and Report of Clinical Cases”
by Nark-Kyoung Rho, Hyun-Jo Kim, Hyun-Seok Kim and Won Lee
J. Clin. Med. 2024, 13(2), 440; https://doi.org/10.3390/jcm13020440
Full text available online: https://www.mdpi.com/2077-0383/13/2/440

4. “Three-Dimensional Printing in Breast Reconstruction: Current and Promising Applications”
by Horacio F. Mayer, Alejandro Coloccini and José F. Viñas
J. Clin. Med. 2024, 13(11), 3278; https://doi.org/10.3390/jcm13113278
Full text available online: https://www.mdpi.com/2077-0383/13/11/3278

5. “Reconstruction of Craniomaxillofacial Bone Defects with 3D-Printed Bioceramic Implants: Scoping Review and Clinical Case Series”
by Maarten Verbist, Anne-Laure Vandevelde, Joris Geusens, Yi Sun, Eman Shaheen and Robin Willaert
J. Clin. Med. 2024, 13(10), 2805; https://doi.org/10.3390/jcm13102805
Full text available online: https://www.mdpi.com/2077-0383/13/10/2805

6. “Bioactive Dressing: A New Algorithm in Wound Healing”
by Gianmarco Polverino, Francesca Russo and Francesco D’Andrea
J. Clin. Med. 2024, 13(9), 2488; https://doi.org/10.3390/jcm13092488
Full text available online: https://www.mdpi.com/2077-0383/13/9/2488

7. “Our Experience in Diagnosing and Treating Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL)”
by Gon Shoham, Oriana Haran, Roei Singolda, Ehab Madah, Ada Magen, Orit Golan, Tehillah Menes, Ehud Arad and Yoav Barnea
J. Clin. Med. 2024, 13(2), 366; https://doi.org/10.3390/jcm13020366
Full text available online: https://www.mdpi.com/2077-0383/13/2/366

8. “A Multidisciplinary Approach to End-Stage Limb Salvage in the Highly Comorbid Atraumatic Population: An Observational Study”
by Karen R. Li, Christian X. Lava, Monique B. Neughebauer, Rachel N. Rohrich, Jayson Atves, John Steinberg, Cameron M. Akbari, Richard C. Youn, Christopher E. Attinger and Karen K. Evans
J. Clin. Med. 2024, 13(8), 2406; https://doi.org/10.3390/jcm13082406
Full text available online: https://www.mdpi.com/2077-0383/13/8/2406

9. “Ultrasound in Microsurgery: Current Applications and New Frontiers”
by Rachel Cowan, Gursimran Mann and Ara A. Salibian
J. Clin. Med. 2024, 13(12), 3412; https://doi.org/10.3390/jcm13123412
Full text available online: https://www.mdpi.com/2077-0383/13/12/3412

10. “Challenges in Autologous Breast Reconstruction: A Review of Recommendations”
by Lauren M. Sinik and Meredith S. Collins
J. Clin. Med. 2024, 13(4), 971; https://doi.org/10.3390/jcm13040971
Full text available online: https://www.mdpi.com/2077-0383/13/4/971

Special Issues:

Microsurgery: Current and Future Challenges
Guest Editor: Dr. Matthias Aitzetmüller-Klietz
Submission deadline: 25 June 2025

“Hand Surgery Clinical Advances and Practice Updates
Guest Editor: Dr. Guy Rubin
Submission deadline: 31 July 2025

Clinical Progress of Mastectomy and Breast Reconstruction Surgery
Guest Editors: Dr. Antoine L. Carre and Dr. Mouchammed Agko
Submission deadline: 28 August 2025

Recent Advances in Facial Palsy Management
Guest Editor: Dr. Ruben Yap Kannan
Submission deadline: 30 September 2025

3 April 2025
Meet Us at the 62nd ERA Congress, 4–7 June 2025, Vienna, Austria


MDPI is pleased to announce our participation in the 62nd ERA Congress, which will be held from 4 to 7 June 2025 in Vienna, Austria.

The 62nd ERA Congress will revolve around the theme of “Game Changers in Nephrology”. The seven main tracks can be explored via the following link: https://www.era-online.org/events/vienna-2025/scientific-programme/.

The following MDPI journals will be represented:

If you are attending 62nd ERA Congress, we invite you to visit us at booth X3.380. Our representatives, Mr. Peter Roth and Dr. Jennie Xu, will be available to discuss publishing opportunities, the benefits of open access, and our commitment to advancing geosciences research.

For more information about the conference, please visit its official website: https://www.era-online.org/events/vienna-2025/.

2 April 2025
MDPI INSIGHTS: The CEO's Letter #21 - Annual Report, Swiss Consortium, IWD, ICARS, Serbia

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

MDPI Releases 2024 Annual Achievements Report

I’m pleased to share the release of MDPI’s 2024 Annual Achievements Report, which reflects our commitment to efficiency, transparency, and excellence in scholarly communication. The report showcases key themes related to our growth (highlighting our workforce expansion, new offices, journal milestones), excellence (editorial and publishing advancements), people (talent development and training), and community (partnerships, conferences, and outreach).

MDPI continues to build connections and drive scientific progress

Our mission remains clear: to support researchers worldwide by delivering an efficient, high-quality publishing experience while strengthening the global Open Access (OA) movement.

Advancing Open Access: A Global Knowledge Hub

In 2024, we published 238,000 peer-reviewed OA articles, reaching over 25 million downloads. This reinforces MDPI’s role as a global knowledge hub, breaking down barriers to access and ensuring that high-quality research is freely available to everyone. As part of the OA movement, we are actively democratizing knowledge, making scientific advancements accessible to researchers, policymakers, educators, and the public, without the restrictions of traditional paywalls.

Expanding our Workforce and Strengthening Research Integrity

Our global presence grew in 2024 with the opening of a new Seoul office, and our workforce expanded to 6,650 staff across 21 offices. This reflects our continued growth mindset and investment in global accessibility. We also continued to take a proactive stance on our commitment to research integrity, tripling our team in this area and joining STM’s Integrity Hub and United2Act. This means more rigorous quality control, stronger safeguards, and collaboration with global initiatives to detect and combat unethical publishing practices at an industry level. Our growth is about reinforcing our role as a trusted, ethical, and accessible publishing platform for researchers worldwide.

Growing Partnerships and Impact in Scholarly Communication

MDPI’s partnerships continue to thrive, with over 900 institutional collaborations, including a landmark agreement with ZB MED in Germany, covering more than 100 universities. Additionally, more than 90% of evaluated MDPI journals have been accepted into Web of Science, including 60 new acceptances in 2024, with nearly 300 journals expected to receive a Journal Impact Factor in 2025. In the same period, 37 MDPI journals were accepted into Scopus, bringing our total indexed titles to 306. Most importantly, 95% of authors rate their experience with MDPI as excellent or good – an achievement that underscores our dedication to serving the research community.

I encourage you to read through our Annual Report, which highlights these milestones and our vision for the future. Thank you for being part of MDPI’s journey in advancing open science.

Impactful Research

MDPI Renews Partnership with CSAL to Support Swiss Universities

I am pleased to announce the renewal of our partnership with the Consortium of Swiss Academic Libraries (CSAL) for 2025. This extension reinforces MDPI's dedication to advancing open science through transparency, efficiency, and collaboration.

Our renewed agreement with CSAL strengthens support for Swiss universities, ensuring that gold open access publishing remains both accessible and affordable for researchers across Switzerland. Among the institutions participating in this agreement are ETH Zurich and EPFL Lausanne, along with 20 other leading institutions, further expanding the reach and impact of our collaborative efforts.

To date, over 3.9 million researchers have published their findings in MDPI journals, a testament to our role in enhancing Switzerland's position as a hub for university education and research.

Inside MDPI

Celebrating International Women's Day: Accelerating Action

In honour of International Women's Day, MDPI embraced the theme “Accelerate Action,” a global call to advance women's progress by implementing effective strategies and resources. As part of our commitment, we highlighted how open access publishing empowers female voices in research and academia.

Throughout March, we featured original blogs authored by MDPI’s female contributors, showcasing the successes of our journals and employees, and addressing pressing topics such as women's health.

“Open Access supports women in education”

Women Accelerating Action Outside of MDPI

MDPI employee Ana Zdravkovic is accelerating action outside of her MDPI role as a Production Assistant. Working with like-minded women at the award-winning Belgrade-based organization UZOR OsnaŽene (meaning ‘empowered women’), they identify serious flaws in cybersecurity, and help protect women and children against online predators by providing evidence to improve legislation and laws around cyber-attacks.

In this article, we interview Ana, celebrating the important and inspiring work that she and the organisation do.

How Open Access Supports Women in Education

Every day, women and girls face barriers in education or career progression. This is caused by a range of factors, including social expectations, poverty, and poor infrastructure.

Quality opportunities and participation in the education system by women is essential to achieving equality and fulfilling their human rights.

Here, we examine how Open Access supports women in education by removing barriers and ensuring that vital research is accessible.

Recent Advancements in Research on Endometriosis

March is Endometriosis Action Month. Endometriosis is a medical condition affecting women and young girls of reproductive age, often causing symptoms such as severe pelvic pain, irregular periods, and infertility.

More research on endometriosis is still urgently needed.

This research will help develop efficient diagnoses and better treatment for those struggling with the condition.

In this article, we explore what endometriosis is and discuss the latest research advancements on the disease.

We also curated a selection of MDPI journals, articles, and Special Issues focusing on gender equity, women in the workplace, and women’s health.​ Find out more about these by visiting our IWD – Accelerate Action landing page.

As I reflect on the month of March and International Women’s Day, I would like to take a moment to recognize and thank all of the incredible women at MDPI for your dedication to democratizing knowledge and shaping open access. Your contributions are invaluable, and they continue to shape the future of MDPI.

Coming Together for Science

The International Conference on Advanced Remote Sensing (ICARS 2025)

The International Conference on Advanced Remote Sensing (ICARS 2025) took place from 26–28 March 2025, in Barcelona, Spain. It was chaired by Prof. Dr. Fabio Tosti from the Faringdon Research Centre for Non-Destructive Testing and Remote Sensing (UK), Prof. Dr. Andrea Benedetto from University Roma Tre (Italy), and Prof. Dr. Luis Ángel Ruiz from Universitat Politècnica de València (UPV, Spain).

Over three days, the conference explored innovations in Earth and environmental sciences, engineering advancements, and practical applications in biological and agricultural fields.

I am pleased to share that the 1st edition of ICARS 2025 was a great success, with 133 attendees out of 146 registrations. The event featured 43 short talks, 64 posters, and 103 accepted abstracts, along with nine keynote speakers and a major panel with five expert panellists.

Over 60 attendees joined the conference dinner, and the event received outstanding feedback.

The main goal of ICARS2025 was to cover how advanced remote sensing technologies are transforming our approach to global challenges.

Awards

Four awards were presented at the conclusion of the conference, sponsored by the journal Remote Sensing: Best Poster Award (€400), Best Oral Presentation Award (€400), and two Early Career Researcher Awards (1st prize: €600 and 2nd prize: €200).

Thank you to our Partnering Societies

We are grateful for the support of our four partnering societies and nine media partners, who played an important role in promoting the conference. Special thanks to our partnering societies: the European Federation of Geologists (EFG), Geoscience Energy Society of Great Britain (GESGB), Asociación Española de Teledetección (AET) – the Spanish Association of Remote Sensing, and the International Society for Digital Earth (ISDE).

Upcoming In-Person Event

31 March–2 April 2025
Plants 2025: From Seeds to Food Security
Location: Barcelona, Spain

This event will gather plant scientists to discuss the latest research on how to feed a growing population while maintaining a sustainable agro-ecosystem.

Find more upcoming MDPI events here.

Closing Thoughts

MDPI Serbia Salon 2025: A Gathering of Academic Excellence

On Tuesday, 18 March, we successfully concluded our first MDPI Serbia Salon in Belgrade. This event provided a great opportunity to showcase MDPI’s achievements, strengthen connections with the Serbian academic community, and highlight our role as the largest publisher in Serbia. We were honoured to welcome Prof. Dr. Sergej M. Ostojić, Editor-in-Chief of MDPI journal Clinical Bioenergetics, as a guest speaker.

Over the past five years, MDPI has experienced continuous growth in Serbia, with an increasing number of publications, an expansion of Editorial Board memberships, and a greater number of active peer reviewers. The Salon allowed us to express our thanks to the Serbian research community while gathering feedback from attendees representing several major universities.

Discussion topics

As part of the event, I delivered an opening speech highlighting MDPI’s achievements and direction.

The event featured presentations from MDPI colleagues, including discussions on open science, publishing ethics, and our achievements in Serbia.

A special thank-you to all our MDPI presenters, panellists, and organizers who made his event a success. I hope the MDPI Serbia Salon becomes a tradition for years to come, creating connections within the Serbian research community.

Visit to the Science Fund of Serbia and The Ministry of Science

During my visit to Belgrade, I had the opportunity to join my colleagues Emir Ramadani (Operations Manager) and Nevena Blagojev (Journal Relations Manager) in meetings with the Science Fund of Serbia and the Ministry of Science, where we received strong support for our work in Serbia.

Both organizations highly value our presence in and commitment to Serbia, where we employ over 640 staff across our two offices in Belgrade and Novi Sad. We take great pride in creating job opportunities and supporting the community in Serbia.

“There’s a lot of exciting activity happening in MDPI Serbia”

Speaking with our Serbian Colleagues

Finally, I had the opportunity to speak with our Serbian colleagues about our initiatives to expand and to improve our marketing & communication and public relations activities.

It was great to have an open discussion with colleagues – both in person and with the hundreds who joined online.

This visit to Belgrade had been a long time coming for me. Serbia is our largest operation in Europe and there’s a lot of exciting activity happening in MDPI Serbia, including the launch of a new office floor in Novi Sad and the growth and expansion of our teams.

I look forward to returning soon and continuing to support our colleagues across our Serbian offices.

Stefan Tochev
Chief Executive Officer
MDPI AG

1 April 2025
Meet us at the 11th Congress of the European Academy of Neurology, 21–24 June 2025, Helsinki, Finland


MDPI will be attending the 11th Congress of the European Academy of Neurology, which will be held in Helsinki, Finland, from 21 to 24 June 2025. The EAN Congress 2025 is organized by the European Academy of Neurology. Its exciting overarching theme of neurology within society sets the scene for an unforgettable congress and is highly relevant to our practice as neurologists, given our crucial role as clinicians—and in many cases neuroscientists—in addressing the huge burden of neurological disorders. To have an impact, we must work with many other stakeholders and specialties, and we look forward to welcoming many of them to the home of neurology in 2025. As usual, the overarching theme will serve as a common thread throughout all the invited content of our congress, from workshops to plenary sessions.

The following MDPI journals will be represented:

If you plan to attend the conference, please visit our booth #E48. Our delegates look forward to meeting you in person and answering any questions that you may have. For more information about the conference, please visit the following website: https://www.ean.org/congress2025.

30 March 2025
Journal of Clinical Medicine | Editor-in-Chief and Section Editors-in-Chief Annual Meeting Held on 17 February 2025


Recently, Journal of Clinical Medicine (JCM, ISSN: 2077-0383) held the Editor-in-Chief and Section Editors-in-Chief Annual Meeting on 17 February 2025, 8:30–10:00 CET. This significant event was hosted by the Editor-in-Chief, Prof. Dr. Kent Doi, and fifteen Section Editors-in-Chief were in attendance, each bringing their unique expertise and insights. We are grateful for the support of all attendees. This meeting presented an opportunity for us to come together to review the journal’s past developments and look forward to a better year.

We reviewed and discussed the following topics with the attendees:

  • An overview of the journal’s performance in 2024;
  • The current Section status, a new Section established, and hot topic data;
  • Marketing activities, virtual conferences, society cooperation, journal awards, and social media promotion.

The following information was covered in the discussion:

  • Currently, the publication and citation data of the journal are satisfactory. In 2025, with the aim of enhancing the journal’s impact factor, the Editorial Board Members put forward suggestions regarding, for example, the types of submissions, the peer-review process, and setting goals for different Sections;
  • Marketing promotion activities were discussed. Members showed their interest in the upcoming International Online Conference on Clinical Medicine (IOCCM) 2025. The registration for attendees is completely free of charge. We are calling for speakers and topic suggestions from attendees;
  • The Editorial Board Members gave detailed suggestions on how to strengthen cooperation with societies to increase the exposure of the journal and promote wider scholarly communication.

Attendee list (Sections are ordered alphabetically, in no particular order):

  • Prof. Dr. Kent Doi (Editor-in-Chief), Department of Acute Care Medicine, University of Tokyo, Tokyo, Japan;
  • Prof. Dr. Luis Garcia-Marcos (“Clinical Pediatrics” Section Editor-in-Chief), Respiratory and Allergy Units, Arrixaca Children’s University Hospital, University of Murcia, Murcia, Spain;
  • Dr. Stefanos Bonovas (“Clinical Research Methods” Section Editor-in-Chief), 1 Department of Biomedical Sciences, Humanitas University, Milan, Italy; 2 IRCCS Humanitas Research Hospital, Milan, Italy;
  • Prof. Dr. Gregory Y. H. Lip (“Cardiology” Section Editor-in-Chief), 1 Price-Evans Professor of Cardiovascular Medicine, University of Liverpool, Liverpool, UK; 2 Distinguished Professor, Aalborg University, Aalborg, Denmark;
  • Prof. Dr. Mario Plebani (“Clinical Laboratory Medicine” Section Editor-in-Chief), Department of Laboratory Medicine, University-Hospital of Padova, Padova, Italy;
  • Prof. Dr. Francisco Guillen-Grima (“Epidemiology & Public Health” Section Editor-in-Chief), 1 Department of Preventive Medicine, Clinica Universidad de Navarra, University of Navarra, Pamplona, Spain; 2 Navarra Medical Research Institute (IdiSNA), Pamplona, Spain; 3 Center for Biomedical Research Network Epidemiology and Public Health, Madrid, Spain; 4 Department of Health Sciences, Public University of Navarra, Pamplona, Spain;
  • Prof. Dr. Michael Christ (“Emergency Medicine” Section Editor-in-Chief), Emergency Department, Luzerner Kantonsspital, Luzern, Switzerland;
  • Prof. Dr. Hidekazu Suzuki (“Gastroenterology & Hepatopancreatobiliary Medicine” Section Editor-in-Chief), Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan;
  • Dr. Carlo Finelli (“Hematology” Section Editor-in-Chief), 1 Italian MDS Foundation (FISIM - ETS), Bologna, Italy; 2 IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy;
  • Prof. Dr. Karim Bendjelid (“Intensive Care” Section Editor-in-Chief), CardioVascular Unit, Intensive Care Division, Geneva University Hospitals, Switzerland;
  • Prof. Dr. Robert Flisiak (“Infectous Diseases” Section Editor-in-Chief), Department of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, Poland;
  • Prof. Dr. Icro Maremmani (“Mental Health” Section Editor-in-Chief), Vincent P. Dole Dual Disorder Unit, Institute of Behavioural Sciences, Pisa, Italy;
  • Prof. Dr. Alberto Signore (“Nucelar Medicine & Radiology” Section Editor-in-Chief), Department of Surgical-Medical Sciences and Translational Medicine, University of Rome “Sapienza”, Rome, Italy;
  • Prof. Dr. Eyal Sheiner (“Obstetrics & Gynecology” Section Editor-in-Chief), Department of Obstetrics and Gynecology, Soroka University Medical Center, Beersheba, Israel;
  • Dr. Nicholas David Clement (“Orthopedics” Section Editor-in-Chief), Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK;
  • Dr. Sukhwinder Singh Sohal (“Pulmonology” Section Editor-in-Chief), Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, Australia.

The latest official CiteScore (2023 Scopus data) for the Journal of Clinical Medicine is 5.7, ranking 80/636 (Q1) in the “General Medicine” category. The current Impact Factor of JCM is 3.0 (2023), ranking 59/329 (Q1) in the “Medicine, General, and Internal” category. To access more journal statistics, please click here.

JCM Editorial Office

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