Clinical Advances in the Management and Treatment of Obesity

Dear Colleagues,

Obesity is a chronic, relapsing, and multifactorial disease that affects billion of people worldwide. It is characterised by several complications, involving multiple organs and systems. The numerous pathophysiological processes involved and the cumulative multi-system damage may lead to a generalised impairment of the organism, resulting in reduced functional capacity and progressive disability.

In people with obesity, functional evaluation with cardiopulmonary exercise testing and a strength assessment may reveal specific ventilatory, cardiovascular and peripheral limitations. From a therapeutic point of view, the tools are diverse and rely on diet therapy, behavioural therapy, exercise, and bariatric surgery. However, most of the information on the effectiveness of these treatments is based on a primary outcome, namely weight loss, and secondarily on some cardio-metabolic or osteo-articular complications.

This Special Issue aims to draw attention to therapeutic innovations that demonstrate how the treatment of obesity can go beyond weight loss and provide an overall health benefit to people suffering from this disease. In particular, the focus is on the beneficial effects of various therapeutic strategies, including structured exercise, on obesity-related functional limitations. Priority will be given to papers demonstrating the role of exercise prescription alone or in combination with dietary, pharmacological and surgical therapy on improving obesity complications. This Special Issue will also welcome papers dealing with the effects of all the therapeutic strategies on physical fitness and functional limitations. In addition, papers presenting innovative approaches in the treatment of obesity and personalized medicine will complete the spectrum of interest of this Special Issue.

The goal of this project is to show that the benefits of obesity therapy go beyond weight loss and that, as a multifactorial condition, all aspects of this disease (including functional ones) must be addressed by therapeutic interventions.

Dr. Francesca Battista
Guest Editor

Manuscript Submission Information

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• obesity
• therapy
• weight loss
• diet
• surgery
• exercise
• personalized medicine