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New Perspectives on Interventional Treatment of Coronary Artery Disease

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 97

Special Issue Editor


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Guest Editor
Department of Medicine, School of Medicine, University of Arizona, Tucson, AZ, USA
Interests: complex coronary intervention; coronary bifurcation; new frontiers in interventional cardiology; calcified lesions, chronic total occlusions, high-pressure balloons; intracoronary lithotripsy

Special Issue Information

Dear Colleagues,

This Special Issue arrives at a pivotal moment in cardiology, as the field of percutaneous coronary intervention (PCI) evolves beyond its foundational goal of restoring vessel patency. While drug-eluting stents remain a cornerstone, we are witnessing a paradigm shift toward a more nuanced, patient-centered, and physiology-guided approach. This collection of articles seeks to define this "new perspective," moving from a focus solely on anatomy to a holistic integration of ischemia assessment, plaque morphology, and functional significance.

Contributions explore cutting-edge themes: the maturation of intravascular imaging (OCT, IVUS) to optimize stent deployment and characterize vulnerable plaque; the definitive role of fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) in guiding revascularization decisions; and the promise of bioresorbable scaffolds and targeted pharmacotherapies. Furthermore, we delve into the management of complex scenarios—chronic total occlusions, left main disease, coronary bifurcation, severely calcified lesions, and diabetic patients—highlighting tailored strategies. Furthermore, the advent of super high-pressure balloons and intracoronary lithotripsy has revolutionized the treatment of calcified lesions. Ultimately, this issue underscores that the future of interventional cardiology lies in leveraging technology not just to open arteries but to deliver the right intervention for the right lesion in the right patient, thereby improving long-term clinical outcomes and quality of life.

Prof. Dr. Mohammad Reza Movahed
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • complex coronary intervention
  • coronary bifurcation
  • new frontiers in interventional cardiology
  • calcified lesions
  • chronic total occlusions
  • high-pressure balloons
  • intracoronary lithotripsy

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Published Papers

This special issue is now open for submission.
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