From Histology to Clinical Immunology: Integrated Diagnosis in Oral and Maxillofacial Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".
Deadline for manuscript submissions: 20 August 2026 | Viewed by 143
Special Issue Editor
2. Department of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, Rome, Italy
Interests: oral health; biomaterials; dental tissues; histology; immunofluorescence; dental materials
Special Issue Information
Dear Colleagues,
Advances in clinical immunology are rapidly reshaping the diagnosis of oral and maxillofacial diseases, particularly where conventional histopathology alone is insufficient to resolve overlapping phenotypes and heterogeneous inflammatory patterns. Despite progress, core challenges remain: distinguishing immune-mediated from infectious or reactive conditions, identifying actionable biomarkers that correlate with disease activity and prognosis, and standardizing immune-based assays across laboratories and clinical settings. This Special Issue aims to consolidate current research status and accelerate solutions by integrating clinical immunology with histology and immunopathology (including immunohistochemistry and immunofluorescence) to improve diagnostic precision and patient stratification. We welcome submissions spanning mechanistic studies, diagnostic algorithms, and clinicopathologic correlation in autoimmune, inflammatory, premalignant, and malignant conditions affecting oral mucosa, salivary glands, jawbone, and related tissues. We also encourage methodological papers on assay validation, reproducibility, and reporting standards. We invite colleagues to contribute original research and reviews that advance integrated diagnostics in this field.
Dr. Fabiana Nicita
Guest Editor
Manuscript Submission Information
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Keywords
- clinical immunology
- histology
- immunopathology
- immune-mediated oral disease
- biomarkers
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