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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thoracic Surgery: Current Practice and Future Directions: 2nd Edition

edited by

Dania Nachira

submission deadline 15 Jun 2026 | 4 articles | Viewed by 3516 | Submission Open

Keywords: NSCLC; mediastinum; thymoma; esophageal disease; immunotherapy; new technologies; minimally invasive surgery; VATS; RATS

(This special issue belongs to the Section Respiratory Medicine)

Key Advances in the Treatment of the Critically Ill: 3rd Edition

edited by

Spyros D. Mentzelopoulos

submission deadline 15 Jun 2026 | 3 articles | Viewed by 3478 | Submission Open

Keywords: respiration; artificial ventilation; prone positioning; respiratory distress syndrome; respiratory insufficiency; cardiac arrest; induced hypothermia; amiodarone; vasopressin; steroids; epinephrine; trauma; injuries; tranexamic acid; sepsis; antibiotics; extracorporeal membrane oxygenation; extracorporeal CPR; blood purification

(This special issue belongs to the Section Intensive Care)

Emergency Surgery: Clinical Updates and New Perspectives

edited by

Bruno Cirillo

submission deadline 15 Jun 2026 | 1 articles | Viewed by 2950 | Submission Open

Keywords: emergency surgery; trauma surgery; acute abdomen; hernia emergencies; surgical decision making; perioperative care; damage control surgery; emergency management; critical care surgery; multidisciplinary approach

(This special issue belongs to the Section Emergency Medicine)

New Clinical Advances in Pediatric Asthma

edited by

Davor Plavec

submission deadline 15 Jun 2026 | 3 articles | Viewed by 2797 | Submission Open

Keywords: pediatric asthma; clinical management; treatment advances; diagnostic advances; biologic therapy; inhaled steroids; control of asthma; exacerbation prevention; quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Updates on Valvular Heart Diseases: A New Era in Personalized Treatment

edited by Massimiliano Mariani

submission deadline 15 Jun 2026 | 3 articles | Viewed by 2753 | Submission Open

Keywords: valvular heart disease; structural heart intervention; imaging in valve disease; interventional echocardiography; minimally invasive cardiac surgery; aortic valve intervention; tricuspid valve intervention; valve intervention in GUCH; patient-specific therapy; advanced diagnostic techniques; gutting-edge cardiac imaging; catheter-based interventions; innovative cardiac therapies

(This special issue belongs to the Section Cardiology)

Gender Differences and Diversity in the Treatment of Gastric Cancer and Other Malignancies

edited by Claus Schildberg and Frank Meyer

submission deadline 15 Jun 2026 | 2 articles | Viewed by 2482 | Submission Open

Keywords: gastric cancer; other cancers; other treatment; gender differences; diversity; new challances

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Interventional Cardiology: Recent Developments and Future Challenges

edited by

Andreas Mitsis

and George Kassimis

submission deadline 15 Jun 2026 | 2 articles | Viewed by 2028 | Submission Open

Keywords: percutaneous coronary intervention (PCI); drug-eluting stents (DES); high risk percutaneous coronary intervention (CHIP); chronic total occlusions (CTO); intravascular imaging (IVUS; OCT); coronary physiology (FFR; iFR); antiplatelet therapy; complex coronary interventions; mechanical circulatory support (MCS)

(This special issue belongs to the Section Cardiology)

Congenital Heart Diseases: Epidemiology, Treatment and Lifelong Support

edited by Sebastian Freilinger,

Renate Oberhoffer-Fritz

Harald Kaemmerer

and Oliver Dewald

submission deadline 15 Jun 2026 | 3 articles | Viewed by 1672 | Submission Open

Keywords: congenital heart disease (CHD); adults with CHD; epidemiology; comorbidities; intervention; surgical treatment; psychological aspects; quality of life (QoL); risk factors; rehabilitation; health promotion; prevention; health literacy; physical activity; lifelong support

(This special issue belongs to the Section Cardiology)

Clinical Advances in Cancer Imaging

edited by

Paul-Andrei Ștefan

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1492 | Submission Open

Keywords: pelvic oncology; cancer imaging; CT; MRI; tumor staging; treatment response; morphological criteria; gynecologic cancer; bladder cancer; rectal cancer; artificial intelligence; radiomics; texture analysis; image biomarkers; clinical imaging

(This special issue belongs to the Section Oncology)

Novel Diagnostic and Therapeutic Perspectives in Systemic Sclerosis

edited by Mislav Radić

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1344 | Submission Open

Keywords: systemic sclerosis; biomarkers; diagnosis; treatment; diagnostic imaging technique; early detection

(This special issue belongs to the Section Immunology & Rheumatology)

Perioperative Management in Thoracic Surgery: Current Advances and Future Perspectives

edited by

Roberto Cascone

and

Alfonso Fiorelli

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1278 | Submission Open

Keywords: thoracic surgery; perioperative care; ERAS; minimally invasive surgery; interventional pulmonology; preoperative assessment; postoperative management; surgical outcomes; multidisciplinary approach; technology in surgery

(This special issue belongs to the Section Respiratory Medicine)

New Advances of Infectious Disease Epidemiology

edited by

Francisco Guillen-Grima

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1210 | Submission Open

Keywords: infectious disease epidemiology; genomic sequencing; computational modeling; collaborative surveillance; digital epidemiology; one health; pandemic intelligence; public health data integration; emerging pathogens; epidemiologic insights

(This special issue belongs to the Section Epidemiology & Public Health)

Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition

edited by

Lorenzo Ridola

, Stefania Gioia and

Silvia Nardelli

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1183 | Submission Open

Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiac Arrest: Strategies, Innovations, and Improvements in Outcomes

edited by

Kei Hayashida

submission deadline 15 Jun 2026 | Viewed by 1117 | Submission Open

Keywords: cardiac arrest; cardiopulmonary resuscitation; post-cardiac arrest syndrome; neurological outcomes

(This special issue belongs to the Section Cardiology)

Traumatic Brain Injury: Clinical Diagnosis and Management

edited by Alessio Caccioppola

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1059 | Submission Open

Keywords: glasgow coma scale; intracranial pressure monitoring; traumatic brain injury; diffuse axonal injury; post-traumatic epilepsy; decompressive craniectomy; neuromonitoring

(This special issue belongs to the Section Brain Injury)

Clinical Diagnosis and Management of Erectile Dysfunction

edited by Maurizio De Rocco Ponce and

Giuseppe Grande

submission deadline 15 Jun 2026 | 1 articles | Viewed by 818 | Submission Open

Keywords: erectile dysfunction; clinical management; cardiovascular disease; penile prosthesis; personalized medicine; hipogonadism

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations

edited by

Akshay Kumar

and

Mohamed Rahouma

submission deadline 15 Jun 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology

(This special issue belongs to the Section Cardiovascular Medicine)

Innovations in Infertility Treatment and Assisted Reproductive Technologies (ARTs)

edited by Diana Alecsandru

submission deadline 15 Jun 2026 | Viewed by 493 | Submission Open

Keywords: infertility; assisted reproductive technology (ARTs); fertility preservation; in vitro fertilization (IVF); reproductive endocrinology

(This special issue belongs to the Section Obstetrics & Gynecology)

Aortic Surgery: State of the Art and Future Directions

edited by

Dimos E. Karangelis

submission deadline 15 Jun 2026 | 2 articles | Viewed by 405 | Submission Open

Keywords: aortic surgery; aortic aneurysm; aortic dissection; aortic arch; biomaterials; endovascular approach; FET; TEVAR

(This special issue belongs to the Section Cardiovascular Medicine)

Current Challenges and Opportunities in Assisted Reproductive Technologies

edited by Andrea Milostić-Srb and

Davor Jezek

submission deadline 15 Jun 2026 | Viewed by 291 | Submission Open

Keywords: artificial reproductive technologies; ART; mental health effect on ART; IVF; AI in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Surgical Management of Vascular Diseases: Challenges and Innovations in the 21st Century

edited by Reinhardt T. Grundmann

submission deadline 15 Jun 2026 | Viewed by 255 | Submission Open

Keywords: abdominal aortic aneurysm; carotid stenosis; peripheral vascular disease; endovascular therapy; open surgery; vascular disease and cancer outcomes; clinical trial; meta-analysis; surgical innovation

(This special issue belongs to the Section Cardiovascular Medicine)

Skin Cancer: From Diagnosis to Personalized Treatment

edited by

Anthony J. Dixon

submission deadline 15 Jun 2026 | Viewed by 236 | Submission Open

Keywords: immunotherapy; neoadjuvant; melanoma; cutaneous sarcoma; merkel cel tumor; risk assessment; combination therapy; surgery

(This special issue belongs to the Section Dermatology)

Clinical Advancements in Foot and Ankle Surgery: 2nd Edition

edited by

Ho-seong Lee

submission deadline 15 Jun 2026 | Viewed by 230 | Submission Open

Keywords: flat foot; hindfoot motion; diabetic foot; hallux valgus; foot infection; foot trauma

(This special issue belongs to the Section Orthopedics)

New Advances in Stereotactic Radiosurgery

edited by Shafak S. Aluwini

submission deadline 18 Jun 2026 | 2 articles | Viewed by 2340 | Submission Open

Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery

(This special issue belongs to the Section Oncology)

Gynecologic Oncology: Current Therapies and New Frontiers

edited by Laura Paleari and Mariangela Rutigliani

submission deadline 19 Jun 2026 | 1 articles | Viewed by 864 | Submission Open

Keywords: ovarian cancers; gynecological cancer; drug delivery; AI; screening; new therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)

edited by

Panagiotis Christopoulos

submission deadline 20 Jun 2026 | 9 articles | Viewed by 32474 | Submission Open

Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Trauma Care and Emergency Medicine

edited by

Lothar Andreas Schwarte

Patrick Schober

and

Georgios F. Giannakopoulos

submission deadline 20 Jun 2026 | 5 articles | Viewed by 19924 | Submission Open

Keywords: trauma; trauma care; emergency medicine; pre-hospital; emergency room; intensive care unit

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease

edited by Hirsh D. Trivedi

submission deadline 20 Jun 2026 | 5 articles | Viewed by 13303 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease; MASLD; non-alcoholic fatty liver disease; NAFLD; liver disease; liver fibrosis; metabolic syndrome

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application

edited by

Athina A. Samara

and Alexandros Daponte

submission deadline 20 Jun 2026 | 1 articles | Viewed by 10804 | Submission Open

Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions

(This special issue belongs to the Section Obstetrics & Gynecology)

Latest Advances in Orthodontics

edited by

Giuseppina Laganà

submission deadline 20 Jun 2026 | 5 articles | Viewed by 10115 | Submission Open

Keywords: digital treatment planning; clear aligners; skeletal anchorage; OSAS; artificial intelligence

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Evidence-Based Diagnosis and Clinical Management of Low Back Pain

edited by

William J. Hanney

and

Michael Masaracchio

submission deadline 20 Jun 2026 | 4 articles | Viewed by 9879 | Submission Open

Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care

(This special issue belongs to the Section Clinical Rehabilitation)

AI in Maternal Fetal Medicine and Perinatal Management

edited by Ariel Many

submission deadline 20 Jun 2026 | 5 articles | Viewed by 9461 | Submission Open

Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Trauma and Orthopaedic Surgery

edited by Valerio Pace and Pierluigi Antinolfi

submission deadline 20 Jun 2026 | 5 articles | Viewed by 9329 | Submission Open

Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury

(This special issue belongs to the Section Orthopedics)

Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights

edited by

Shinichi Watanabe

Nobuto Nakanishi

and

Yuki Iida

submission deadline 20 Jun 2026 | 7 articles | Viewed by 9221 | Submission Open

Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors

(This special issue belongs to the Section Clinical Rehabilitation)

Therapies for Heart Failure: Clinical Updates and Perspectives

edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma

submission deadline 20 Jun 2026 | 10 articles | Viewed by 7426 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 20 Jun 2026 | 6 articles | Viewed by 7299 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Clinical Approaches to Breast Cancer Diagnosis and Treatment

edited by

Lorenzo Scardina

submission deadline 20 Jun 2026 | 4 articles | Viewed by 6618 | Submission Open

Keywords: breast cancer; diagnosis; precision medicine; molecular profiling; targeted therapy; breast-conserving surgery; minimally invasive techniques; artificial intelligence; personalized medicine; radiation therapy

(This special issue belongs to the Section Oncology)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 20 Jun 2026 | 4 articles | Viewed by 5487 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 20 Jun 2026 | 5 articles | Viewed by 5138 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

Advances in Diagnosis and Treatment of Urological Cancers

edited by

Davide Campobasso

Stefano Puliatti

and

Daniele Amparore

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5042 | Submission Open

Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics

(This special issue belongs to the Section Nephrology & Urology)

Updates on the Clinical Applications of Dental Restorative Materials

edited by

Vittorio Checchi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5019 | Submission Open

Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation

edited by

Mojca Božič Mijovski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4818 | Submission Open

Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology

(This special issue belongs to the Section Cardiology)

Sepsis: Clinical Advances and Practical Updates

edited by

Paolo Formenti

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4386 | Submission Open

Keywords: sepsis pathophysiology; host immune response; biomarkers for sepsis; early sepsis diagnosis; immunotherapy in sepsis; antimicrobial stewardship

(This special issue belongs to the Section Intensive Care)

Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards

edited by

Mara Carsote

and

Claudiu Nistor

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4229 | Submission Open

Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography

(This special issue belongs to the Section Endocrinology & Metabolism)

Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation

edited by

Francisco J. Povedano-Montero

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3944 | Submission Open

Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3903 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Innovations in Psychosis and Schizophrenia: New Findings and Implications

edited by

Gabriele Nibbio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3767 | Submission Open

Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions

(This special issue belongs to the Section Mental Health)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3481 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

State of the Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3444 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3383 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Displaying special issue 251-300 on page 6 of 32.

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