Urinary Microbiome and Genitourinary System Disorders: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 56

Special Issue Editors


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Guest Editor
Nij Smellinghe Hospital, Compagnonsplein 1, 9202 NN Drachten, The Netherlands
Interests: functional urology; microbiome; neuromodulation
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Guest Editor
Department of Urology, Maastricht University, Maastricht, The Netherlands
Interests: neuro-urology; endourology; urologic surgical procedures; urology; neuromodulation; urinary incontinence; pelvic floor; prostate cancer; urodynamics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Editors are grateful to the many researchers who contributed to the success of the first volume of this issue (https://www.mdpi.com/journal/life/special_issues/Urinary_Microbiome). We are very pleased to announce the second volume of our Special Issue “Urinary Microbiome and Genitourinary System Disorders”.

The urinary microbiome is a newly introduced concept that has attracted the attention of medical researchers. Until recently, the urine of healthy individuals was assumed to be sterile. However, the improvement in bacterial detection methods has debunked this assumption. Recent studies have shown that the bladder contains microbiomes, which are not detectable under standard conditions. Analysis using 16S rRNA sequencing and expanded quantitative urine cultures has provided evidence for the presence of live bacteria in urine. Furthermore, the development of metagenomic sequencing has revealed a unique urinary microbiota that is not detectable using standard culture protocols.

Since its a recent introduction, researchers have conducted many fruitful studies on this phenomenon, changing our perspective toward the role of bacteria in the urinary tract and our perception of genitourinary system health.

A deeper understanding of the urinary microbiome can help us to develop more efficient methods for restoring the microbiota to a healthy composition and providing symptom relief. The modification of the urinary microbiome without antibiotic use can be a possible avenue for future research.

Dr. Mohammad Sajjad Rahnama'i
Prof. Dr. Philip Van Kerrebroeck
Guest Editors

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Keywords

  • microbiome
  • microbiota
  • bacteria
  • 16s-RNA sequencing
  • bladder
  • urinary tract infection
  • urgency
  • incontinence
  • lower urinary tract symptoms (LUTS)

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