Epigenetics, Microbiota, and Food—Shaping Immune Health and Longevity
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 28 November 2025 | Viewed by 31
Special Issue Editor
Interests: microbial ecology; food microbiology; nutrition; epigenetic; diabetes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The goal in longevity research is to increase the healthy years of living. Adequate nutrition is essential for this, and it impacts us even before we are born. Moreover, before birth and during the first years of newborns, contact with various bacteria strains can have a profound impact on a child’s microbiota. It is well known that the diets of parents and even grandparents leave an epigenetic imprint on the offspring, which can have long-lasting effects on health.
As low-grade inflammation is a major factor associated with most age-related diseases, an adequate diet can counteract and even favor longevity. Many food compounds, including epigenetic active plant ingredients such as curcumin, have a direct influence on the microbiota and epigenetic mechanisms. Whereas poor nutrition and nutrient deficiency have harmful effects on immune function, some specific food compounds exhibit important functions as modulators of health.
Through understanding the epigenetic mechanisms of interactions between nutrients, aging, and health, disease prevention approaches could be optimized.
In this Special Issue of Life, we encourage researchers to explore the role of diet, particularly relevant components shaping immune health and longevity, in modulating microRNA expression and epigenetics. We look forward to receiving your contributions to this vital area of research.
Dr. Berit Hippe
Guest Editor
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Keywords
- epigenetics
- nutrigenomics
- aging
- microRNA
- DNA methylation
- diet
- nutrients
- microbiota
- longevity
- natural components
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