Microvascular and Macrovascular Response in Healthy and Critically III
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 45
Special Issue Editors
Interests: intensive care; critical illness; shock; mechanical ventilation; microcirculation; glycocalyx; hemodynamics; fluid responsiveness; cardiovascular responsiveness; aerobic and anaerobic exercise
Interests: environmental extreme and performance; cold stress; heat stress; thermal therapy; neuromuscular performance; calorie restriction; metabolic health; immune system; athletic performance; heart rate variability
Special Issue Information
Dear Colleagues,
The cardiovascular response, encompassing both macrovascular and microvascular components, represents the function of the cardiovascular system as it adjusts to various stimuli that can disrupt normal homeostasis. For the healthy, these stimuli can include a variety of external factors and exercises and various maneuvers, such as passive leg raising, etc. Specific maneuvers or strategies help to assess macrovascular and microvascular reactivity, preload responsiveness, and help to adapt the body to ischaemia/reperfusion and stress in future. Studies show that cardiovascular fitness or adaptation to ischaemia/reperfusion can reduce mortality from all causes.
In various diseases, including those seen in critically ill patients, it is also essential to assess the macrovascular and microvascular reactivity (reserve) and response to various treatment. Research on methods for determining fluid responsiveness, as well as the effects of remote ischemic conditioning, constitutes an important aspect of this topic.
The main aim of the current topic is to collect articles (original research, communications, reviews, and brief reports) addressing state-of-the-art information on microvascular or macrovascular responses to various, acute, or chronic stimuli (external factors, exercise, pharmacological factors, various maneuvers, remote ischemic conditioning, and others) in healthy people and patients with various diseases, including those who are critically ill. Articles addressing (i) microcirculation, endothelial glycocalyx, endothelial function, peripheral perfusion, body temperature and systemic hemodynamic response to external factors, exercise, pharmacologic factors, various maneuvers, remote ischemic conditioning or adaptations, and other stimuli in healthy patients and those with various diseases, including critical illnesses; (ii) knowledge of microvascular, peripheral perfusion, and macrovascular response and its evaluation methods (video microscopy/glycocalyx, plethysmography, laser Doppler flowmetry, eye digital fundus camera, body temperature gradient, etc.) in healthy patients and those with disease, including critical illnesses; (iii) therapies or strategies based on personalized modulation of microcirculation, endothelium, body temperature, and/or systemic hemodynamic are welcome and will be considered for publication.
Prof. Dr. Andrius Pranskunas
Prof. Dr. Marius Brazaitis
Guest Editors
Manuscript Submission Information
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Keywords
- microcirculation
- glycocalyx
- peripheral perfusion
- systemic hemodynamic
- body temperature
- dynamic maneuvers
- remote ischemic conditioning
- exercise
- adaptation
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