Influence of Microbiota on the Brain
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (26 January 2024) | Viewed by 200
Special Issue Editor
Interests: stroke; brain tumor; autism; microbiome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut–brain axis orchestrates a wide range of physiological processes that profoundly affect the immune responses in the brain and intestine. Understanding the mechanisms and pathophysiology of central nervous system diseases (CNS) and modulation of the gut–brain axis could inspire future research for developing effective therapeutic treatment for neurological disorders.
The aim of the present Special Issue is to collect original articles and reviews aimed at highlighting the role of the gut–brain axis in inflammatory and neurological diseases such as stroke, autism, schizophrenia, and traumatic brain injury. The gut microbiota regulates the host immune system, physiology, nutrition, and brain function. Recent research has shown that impaired microbial dysbiosis is associated with CNS disease, and treatment with pharmaceutical or natural products has shown promise in improving their symptoms. Understanding the therapeutic mechanisms underlying inflammatory and metabolomic pathways in the brain and gut including dosage effects, bioactive ingredients, antioxidants activities, and microbiota profile could provide insights for developing effective pharmacological treatment for clinical use.
We welcome articles that elucidate the physiological mechanisms of neurological disorders and pharmacological treatment. This includes articles describing
- How the gut–brain axis is involved in CNS disorders and their pathogenesis;
- Scientific assessments (original articles) on diverse groups of natural products, including isolated metabolites and Chinese and other forms of traditional medicine, showing their effects on the gut–brain axis in neurological diseases.
Dr. Gilbert Aaron Lee
Guest Editor
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Keywords
- gut-brain axis
- central nervous system diseases
- inflammation
- metabolomic pathways
- natural product
- antioxidants activities
- microbiota profile
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