Organogenesis and Regeneration: From Basic Research to Medical Study—2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".

Deadline for manuscript submissions: 30 April 2025

Special Issue Editors


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Guest Editor
1. Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China
2. College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China
Interests: animal development; signal transduction; hematopoiesis; pattern formation
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Guest Editor
Department of Plant Biosecurity, College of Plant Protection, China Agricultural University, Beijing 100193, China
Interests: developmental signaling pathways; organogenesis; Insect development

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Guest Editor
College of Life Science, Tianjin Normal University, Tianjin 300387, China
Interests: regeneration; gene editing

Special Issue Information

Dear Colleagues,

An organ is a multi-cellular organism whose formation requires cell–cell coordination to establish an accurate structure and function. Various cellular behaviors, such as cell division, cell differentiation, cell movement, cell–cell communication, pattern formation, etc., are involved in the process of organogenesis, and all must be tightly controlled. Numerous studies have explored the underlying mechanisms that govern the development and formation of different organs. However, we are still far from fully understanding these processes.

Regeneration is the capacity of adult animals to restore their lost/damaged tissues/organs after injury. This capacity largely differs among species, from whole-body regeneration in Hydra and planarians, body parts—such as the limbs and tail—regeneration in salamanders and Xenopus, to organ—such as the heart—regeneration in adult zebrafish and neonatal mice. Regeneration achieves faithful restoration of tissue/organs in structures and functions and requires precise control.

Organogenesis and regeneration may employ similar molecular and cellular mechanisms, but they also possess their own unique aspects. Deciphering the innate mechanisms of development and regeneration may help explore new therapeutic strategies to benefit human health.

This Life Special Issue “Organogenesis and Regeneration: From Basic Research to Medical Study” will include both original research articles and review articles about organogenesis and regeneration. Basic research to clinic reports are all welcome.

Prof. Dr. Ying Su
Dr. Junzheng Zhang
Prof. Dr. Ju Li
Guest Editors

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Keywords

  • organogenesis
  • regeneration
  • development
  • proliferation
  • differentiation
  • blastema
  • signaling pathway

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This special issue is now open for submission.
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