Zebrafish Models in Marine Drug Discovery

Dear Colleagues,

Marine organisms are a vital source of lead compounds for drugs. Bioactivity evaluation is an indispensable step in drug discovery. However, evaluating the activity of marine natural products is often limited by their low content.

Zebrafish have the unique advantages of a short reproductive cycle, in vitro embryo development, overall embryo transparency, high genetic similarity to humans, easy maintenance, and low cost. As an ideal vertebrate model, zebrafish are widely used in screening the bioactivity of natural active compounds. Furthermore, activity evaluation using zebrafish models requires minimal sample volumes, making them highly suitable for screening the activity and researching the mechanisms of marine natural products.

For this Special Issue, we invite scientists from both academia and industry to submit articles highlighting the application of zebrafish models in the discovery of active marine natural products and the study of their mechanisms of action.

Dr. Xiaobin Li
Dr. Yun Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• marine drugs
• zebrafish model
• active natural product
• bioactivity screening
• mechanism of action
• activity evaluation