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Electrochemical Behavior and Antibacterial Propeties of Complexes

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: closed (1 October 2021) | Viewed by 3375

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Guest Editor
Department of Chemistry and Biochemistry, Mendel University in Brno, CZ-613 00 Brno, Czech Republic
Interests: applied electrochemistry; membrane separation; sensors and biosensors; bioelectrochemistry
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Special Issue Information

Dear Colleagues,

The broad field of application of metal complexes has attracted researchers’ interest, particularly in the synthesis of novel complexes. However, before application, newly synthesized complexes must first be fully characterized. Electrochemistry offers a simple and fast characterization method that can collect significant information about the properties of the synthesized complex. Different electrochemical techniques, such as cyclic voltammetry, coulometry, and pulsed techniques, can be applied to characterize a compound. In fact, many properties of a complex may stem from its electrochemical reactivity and properties, particularly its redox reaction mechanism. Therefore, electrochemical characterization is of high importance in metal complex chemistry. On the other hand, the biological and medical application of metal complexes is of interest, as they can be considered as potential drugs for various treatment purposes, such as bacterial and fungal infection, cancer, etc. In fact, finding new compounds for various medical purposes mostly relies on organometallic compounds and coordination compounds. At present, various modifications are being made for the preparation of different kinds of biologically active compounds with various ligands (e.g., benzimidazole) and bases (e.g., Schiff bases). For the medication of humans and animals, drugs must be nontoxic, and metallic and organometallic coordination and organometallic compounds have shown promising results and proven to be nontoxic in most cases within their doses. In recent times, biologically active coordination and organometallic compounds have had promising uses against antibiotic-resistant bacterial, fungal, and cancer chemoresistant pathogens. Moreover, they can be synthesized in a large scale with a low cost, which can enhance their acceptability as an alternative biologically active drug. To summarize, it can be concluded that these biologically active compounds have a high impact on medical sciences and can be the future drugs in the professional healthcare system with an affordable price.

Dr. Amirmansoor Ashrafi
Guest Editor

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Keywords

  • Complex synthesis
  • Electrochemical characterization
  • Electrochemical behavior
  • Redox reaction mechanism
  • Electrochemical characterization
  • Biological activity
  • Cytotoxic activity
  • Antibacterial activity
  • Antimicrobial activity

Published Papers (1 paper)

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Research

17 pages, 18188 KiB  
Article
Bis(2,2′-bipyridil)Copper(II) Chloride Complex: Tyrosinase Biomimetic Catalyst or Redox Mediator?
by Milan Sýs, Atripan Mukherjee, Granit Jashari, Vojtěch Adam, Amir M. Ashrafi, Miroslav Novák and Lukáš Richtera
Materials 2021, 14(1), 113; https://doi.org/10.3390/ma14010113 - 29 Dec 2020
Cited by 8 | Viewed by 3009 | Correction
Abstract
In this article, construction of amperometric sensor(s) based on screen-printed carbon electrodes covered by thin layers of two types of carbon nanomaterials serving as amplifiers, and containing [Cu(bipy)2Cl]Cl∙5H2O complex is reported. Their performance and biomimetic activity towards two selected [...] Read more.
In this article, construction of amperometric sensor(s) based on screen-printed carbon electrodes covered by thin layers of two types of carbon nanomaterials serving as amplifiers, and containing [Cu(bipy)2Cl]Cl∙5H2O complex is reported. Their performance and biomimetic activity towards two selected neurotransmitters (dopamine and serotonin) was studied mainly using flow injection analysis (FIA). The important parameters of FIA such as working potential, flow rate, and pH were optimized. The mechanism of the catalytic activity is explained and experimentally confirmed. It reveals that presence of hydrogen peroxide plays a crucial role which leads to answer the title question: can presented complex really be considered as a tyrosinase biomimetic catalyst or only as a redox mediator? Full article
(This article belongs to the Special Issue Electrochemical Behavior and Antibacterial Propeties of Complexes)
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