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Mechanical and Biological Properties of Advanced Dental Materials
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Mechanical and Biological Properties of Advanced Dental Materials

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (28 February 2021) | Viewed by 3412

Special Issue Editors

Prof. Sandro Rengo

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Guest Editor
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Via Pansini 5, 80131 Naples, Italy
Interests: dentistry; endodontics; biomaterials
Prof. Francesco Riccitiello

E-Mail Website
Guest Editor
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Via Pansini 5, 80131 Naples, Italy
Interests: dentistry; endodontics; biomaterials
Prof. Dr. Rosa Valletta

E-Mail Website
Guest Editor
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Via Pansini 5, 80131 Naples, Italy
Interests: dentistry; orthodontics; biomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Mechanical and Biological Properties of Advanced Dental Materials have been widely investigated and improved, to meet the main clinical requirements. Typically, dental materials have wide use in several fields of dental sciences, such as conservative dentistry, endodontics, orthodontics, surgery, and periodontics. In recent years, novel and bioactive materials have been used as scaffolds in reconstructive oral surgery, or as filling materials in order to repair/restore damaged tooth tissues. The scientific community is fully committed to developing and characterizing novel dental materials, to better understand their behavior and their potential applications in clinical and surgical cases.

Today, the dental material market includes resin composite, polymers, glass ionomers, ceramics, titanium, zirconia, and silicate cement. Novel biocompatible and bioactive materials are daily reported in the scientific literature, with a specific commitment towards pulp repairing/regeneration, dental/oral tissue engineering, and bone repairing. Additive technologies have produced strong conditions to create novel customized and personalized biomaterials, thus, combining excellent mechanical and biological properties in the same product.

Better knowledge of biological, chemical, physical, and mechanical proprieties of dental materials requires a continuous sharing of the latest research and discoveries.

The aim of this Special Issue is to welcome the most promising and innovative results on biomaterials used in dental applications.

Original research articles, well-designed review articles, and significant preliminary communication are invited and warmly welcome.

Prof. Sandro Rengo
Prof. Francesco Riccitiello
Prof. Rosa Valletta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Dental materials
  • Resin composite
  • Endodontic cement
  • Titanium implant
  • Prosthetic dentistry
  • Orthodontic materials
  • Regenerative dentistry

Published Papers (1 paper)

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Research

14 pages, 1852 KiB  
Article
Spongostan™ Leads to Increased Regeneration of a Rat Calvarial Critical Size Defect Compared to NanoBone® and Actifuse
by Dirk Wähnert, Julian Koettnitz, Madlen Merten, Daniel Kronenberg, Richard Stange, Johannes F. W. Greiner, Christian Kaltschmidt, Thomas Vordemvenne and Barbara Kaltschmidt
Materials 2021, 14(8), 1961; https://doi.org/10.3390/ma14081961 - 14 Apr 2021
Cited by 9 | Viewed by 2948
Abstract
Bone substitute materials are becoming increasingly important in oral and maxillofacial surgery. Reconstruction of critical size bone defects is still challenging for surgeons. Here, we compared the clinically applied organic bone substitute materials NanoBone® (nanocrystalline hydroxyapatite and nanostructured silica gel; n = [...] Read more.
Bone substitute materials are becoming increasingly important in oral and maxillofacial surgery. Reconstruction of critical size bone defects is still challenging for surgeons. Here, we compared the clinically applied organic bone substitute materials NanoBone® (nanocrystalline hydroxyapatite and nanostructured silica gel; n = 5) and Actifuse (calcium phosphate with silicate substitution; n = 5) with natural collagen-based Spongostan™ (hardened pork gelatin containing formalin and lauryl alcohol; n = 5) in bilateral rat critical-size defects (5 mm diameter). On topological level, NanoBone is known to harbour nanopores of about 20 nm diameter, while Actifuse comprises micropores of 200–500 µm. Spongostan™, which is clinically applied as a haemostatic agent, combines in its wet form both nano- and microporous topological features by comprising 60.66 ± 24.48 μm micropores accompanied by nanopores of 32.97 ± 1.41 nm diameter. Micro-computed tomography (µCT) used for evaluation 30 days after surgery revealed a significant increase in bone volume by all three bone substitute materials in comparison to the untreated controls. Clearly visual was the closure of trepanation in all treated groups, but granular appearance of NanoBone® and Actifuse with less closure at the margins of the burr holes. In contrast, transplantion of Spongostan™ lead to complete filling of the burr hole with the highest bone volume of 7.98 ccm and the highest bone mineral density compared to all other groups. In summary, transplantation of Spongostan™ resulted in increased regeneration of a rat calvarial critical size defect compared to NanoBone and Actifuse, suggesting the distinct nano- and microtopography of wet Spongostan™ to account for this superior regenerative capacity. Since Spongostan™ is a clinically approved product used primarily for haemostasis, it may represent an interesting alternative in the reconstruction of defects in the maxillary region. Full article
(This article belongs to the Special Issue Mechanical and Biological Properties of Advanced Dental Materials)
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