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Polymer-Inorganic Nanocomposites: Synthesis, Characterization and Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Composites".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 5996

Special Issue Editor


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Guest Editor
National Institute for Research & Development in Chemistry and Petrochemistry ICECHIM, Bucharest, Romania
Interests: synthesis and characterization of nanocomposites; nanocomposite biopolymer formulations for additive manufacturing/3D printing as well as functionalization of inorganic particles; encapsulation/controlled release of (bio)active substances
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Special Issue Information

Dear Colleagues,

When thinking of advanced materials, we should consider, more or less, the polymer-inorganic nanocomposites.

In recent years, there has been an upsurge of studies related to the development of various nanocomposite materials based on polymer matrixes with incorporated inorganic nanoparticles. Their small size and large surface area make inorganic nanoparticles serious candidates for improving characteristics and favourably affecting the quality of the designed nanocomposites.

Consequently, multidisciplinary research efforts related to polymer science, inorganic chemistry, colloids, material engineering, physics, biology, biotehnology, pharmaceutics and medicine fields have been undertaken to develop suitable complex polymer-inorganic nanocomposite systems that are able to respond to the current needs.

The present Special Issue welcomes contributions in the form of full articles, short communications, or review articles related to the synthesis, characterization and applications of novel polymer-inorganic nanocomposites.

This Special issue will focus on studies related to the design and testing of polymer inorganic nanocomposites based on either natural ocurring polymers, synthetic polymers or semi-synthetic polymers as hosts, with incorporated zero-dimensional to three-dimensional particles of nanoscale dimensions, for diverse applications.

 

Dr. Raluca Ianchis
Guest Editor

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Keywords

  • polymer
  • inorganic particles
  • nanocomposites
  • drug delivery
  • chemical and morphological characterization of nanocomposites

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Published Papers (2 papers)

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Research

18 pages, 3347 KiB  
Article
The Effects of Monomer, Crosslinking Agent, and Filler Concentrations on the Viscoelastic and Swelling Properties of Poly(methacrylic acid) Hydrogels: A Comparison
by Claudia Mihaela Ninciuleanu, Raluca Ianchiş, Elvira Alexandrescu, Cătălin Ionuţ Mihăescu, Cristina Scomoroşcenco, Cristina Lavinia Nistor, Silviu Preda, Cristian Petcu and Mircea Teodorescu
Materials 2021, 14(9), 2305; https://doi.org/10.3390/ma14092305 - 29 Apr 2021
Cited by 34 | Viewed by 3151
Abstract
The present work aims at comparatively studying the effects of the concentrations of a monomer (10–30 wt% based on the whole hydrogel composition), crosslinking agent (1–3 mol% based on the monomer), and reinforcing agent (montmorillonite-MMT, 1–3 wt.% based on the whole hydrogel composition) [...] Read more.
The present work aims at comparatively studying the effects of the concentrations of a monomer (10–30 wt% based on the whole hydrogel composition), crosslinking agent (1–3 mol% based on the monomer), and reinforcing agent (montmorillonite-MMT, 1–3 wt.% based on the whole hydrogel composition) on the swelling and viscoelastic properties of the crosslinked hydrogels prepared from methacrylic acid (MAA) and N,N′-methylenebisacrylamide (BIS) in the presence of K2S2O8 in aqueous solution. The viscoelastic measurements, carried out on the as-prepared hydrogels, showed that the monomer concentration had the largest impact, its three-time enhancement causing a 30-fold increase in the storage modulus, as compared with only a fivefold increase in the case of the crosslinking agent and 1.5-fold increase for MMT in response to a similar threefold concentration increase. Swelling studies, performed at three pH values, revealed that the water absorption of the hydrogels decreased with increasing concentration of both the monomer and crosslinking agent, with the amplitude of the effect of concentration modification being similar at pH 5.4 and 7.4 in both cases, but very different at pH 1.2. Further, it was shown that the increased pH differently influenced the swelling degree in the case of the hydrogel series in which the concentrations of the monomer and crosslinking agent were varied. In contrast to the effect of the monomer and crosslinking agent concentrations, the increase in the MMT amount in the hydrogel resulted in an increased swelling degree at pH 5.4 and 7.4, while at pH 1.2, a slight decrease in the water absorption was noticed. The hydrogel crosslinking density determinations revealed that this parameter was most affected by the increase in the monomer concentration. Full article
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20 pages, 6657 KiB  
Article
Salecan-Clay Based Polymer Nanocomposites for Chemotherapeutic Drug Delivery Systems; Characterization and In Vitro Biocompatibility Studies
by Paula Ecaterina Florian, Madalina Icriverzi, Claudia Mihaela Ninciuleanu, Elvira Alexandrescu, Bogdan Trica, Silviu Preda, Raluca Ianchis and Anca Roseanu
Materials 2020, 13(23), 5389; https://doi.org/10.3390/ma13235389 - 27 Nov 2020
Cited by 11 | Viewed by 2207
Abstract
Salecan is a microbial polysaccharide suitable to obtain hydrogel for biomedical applications due to the excellent hydrophilicity and biocompatibility properties. In this work, Salecan of different concentrations was introduced into polymethacrylic acid (PMAA) in the presence of clay to form novel semi synthetic [...] Read more.
Salecan is a microbial polysaccharide suitable to obtain hydrogel for biomedical applications due to the excellent hydrophilicity and biocompatibility properties. In this work, Salecan of different concentrations was introduced into polymethacrylic acid (PMAA) in the presence of clay to form novel semi synthetic hydrogel nanocomposites systems and loaded afterwards with doxorubicin (DOX). The physical–chemical characteristics of the nanocomposites systems and their effect on the viability, and morphology of MDBK (Madin–Darby bovine kidney), HT-29 human colorectal adenocarcinoma and Colo 205 human colon adenocarcinoma cell lines were investigated. DOX release from the nanocomposite systems, cell up-take and subsequent effect on cell proliferation was also analyzed. It was found that Salecan concentration determined the swelling behavior, structural parameters and morphological features of the nanocomposite systems. The hydrogen bonds strongly influenced the formation of PMAA–Salecan–clay systems, each component bringing its own contribution, thus demonstrating the achievement of an advanced crosslinked network and a more compacted hydrogel nanocomposite morphology. All the synthesized nanocomposites had negligible toxicity to normal MDBK cells and chemoresistent HT-29 cell line, whereas in the case of Colo 205 cells a decrease by 40% of the cell viability was obtained for the sample containing the highest amount of Salecan. This effect was correlated with the lowest pore size distribution leading to highest available specific surface area and entrapped amount of DOX which was further released from the nanocomposite sample. Corroborating all the data it can be suggested that the synthesized nanocomposites with Salecan and clay could be good candidates as vehicles for chemotherapeutic agents. Full article
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