Microarray-Based Platforms and Strategies for the Development of Molecular-Centric Diagnostic Tools
A special issue of Microarrays (ISSN 2076-3905).
Deadline for manuscript submissions: closed (31 July 2015) | Viewed by 11833
Special Issue Editor
Interests: gene expression profiling; diagnostic biomarkers for complex disease; peripheral biomarkers for diagnosis and disease monitoring; peripheral biomarkers for assessing therapeutic efficacy; developing classifiers
Special Issue Information
Dear Colleagues,
The heterogeneous and sometimes overlapping presentation in complex diseases can result in an inability to provide a timely and definitive diagnosis. The clinical practices of gastroenterology (e.g., in the case of Crohn’s disease versus ulcerative colitis) and urology (e.g., in the case of interstitial cystitis versus bladder pain syndrome) offer but two examples among many wherein it is not always possible to provide a clear discrimination between two similar disease presentations. Assessing disease stage or disease progression (e.g., in Parkinson’s disease) can present a similar challenge. These diagnostic ambiguities can ultimately result in less than optimal treatment strategies and, therefore, less than optimal outcomes. In this era of developing a more personalized approached to patient care, the discovery of additional robust (i.e., both sensitive and specific) diagnostic tools to assist the clinician is an absolute priority.
Molecular profiling—specifically those approaches that employ microarray-based platforms—of both patient-derived disease tissues, and also peripheral tissues (e.g., blood, urine, CSF), provides the research community with a formidable set of technologies to bring to bear for the development of these new clinical diagnostic tools. This special issue focuses on all aspects of microarray-based biomarker development for the diagnosis, monitoring, and treatment of complex disease. The issue will emphasize the various microarray-based approaches currently in use across a variety of diseases.
Dr. Stephen J. Walker
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microarrays is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- microarray
- biomarker
- diagnostic
- peripheral biomarker
- personalized medicine
- classifiers
