Acoustofluidics for Chemical, Biological, and Medical Applications

A special issue of Micromachines (ISSN 2072-666X).

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2272

Special Issue Editors


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Guest Editor
School of Instrument Science and Opto-Electronics Engineering, Hefei University of Technology, Hefei 230009, China
Interests: acoustofluidic; acoustic tweezer; acoustic streaming; particles; cells; droplets; bubbles; metamaterials

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Guest Editor
School of Mechanical Engineering, Xi'an Jiao Tong University, Xi'an 710049, China
Interests: acoustofluidic; acoustic tweezer; acoustic streaming; particles; cells; droplets; bubbles; metamaterials

E-Mail Website
Guest Editor
School of Instrument Science and Opto-Electronics Engineering, Hefei University of Technology, Hefei 230009, China
Interests: acoustofluidic; acoustic tweezer; acoustic streaming; particles; cells; droplets; bubbles; metamaterials

Special Issue Information

Dear Colleague,

Acoustofluidic devices use acoustic waves to manipulate the fluid and particles or bubbles in the fluid in a label-free and contactless manner, with biocompatibility, an adjustable wavelength, programmablility, high resolution and precision, and wide ranges of particle size, which accelerate chemical, biological, and medical applications. Reported examples include 2D to 3D manipulation, high-throughput cell sorting, single-cell patterning, tissue engineering and droplet transport, fusion, division, and reactions. Acoustofluidic devices include lithium niobate-based surface acoustic wave (SAW) devices, PZT-based bulk acoustic wave (BAW) devices, and piezoelectric resonant diaphragm devices such as micromachined ultrasonic transducers (MUTs). In this highly exciting and emerging discipline, recent work has demonstrated new concepts, devices, and scenarios, such as manipulating particle of tens of nanometers, fusing acoustic holography, metamaterials and reconfigurable waveguides, hydrogel patterning, acoustofluidic printing, etc. Therefore, this Special Issue aims to showcase research papers, communications, and review articles that focus on novel principles and advanced devices of acoustofluidics, as well as its applications in fundamental biology, analytical chemistry, and medical diagnosis.

Dr. Liang Huang
Prof. Dr. Xueyong (Sean) Wei
Dr. Jingui Qian
Guest Editors

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Keywords

  • acoustofluidic
  • acoustic tweezer
  • acoustic streaming
  • particles
  • cells
  • droplets
  • bubbles
  • metamaterials

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Published Papers (1 paper)

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Research

9 pages, 1850 KiB  
Communication
Swirl-like Acoustofluidic Stirring Facilitates Microscale Reactions in Sessile Droplets
by Huaize Lan, Jingui Qian, Yansong Liu, Shanshan Lu, Bowei Zhang, Liang Huang, Xuefeng Hu and Wei Zhang
Micromachines 2023, 14(4), 837; https://doi.org/10.3390/mi14040837 - 12 Apr 2023
Cited by 3 | Viewed by 1834
Abstract
Sessile droplets play a crucial role in the microreactors of biochemical samples. Acoustofluidics provide a non-contact and label-free method for manipulating particles, cells, and chemical analytes in droplets. In the present study, we propose a micro-stirring application based on acoustic swirls in sessile [...] Read more.
Sessile droplets play a crucial role in the microreactors of biochemical samples. Acoustofluidics provide a non-contact and label-free method for manipulating particles, cells, and chemical analytes in droplets. In the present study, we propose a micro-stirring application based on acoustic swirls in sessile droplets. The acoustic swirls are formed inside the droplets by asymmetric coupling of surface acoustic waves (SAWs). With the merits of the slanted design of the interdigital electrode, the excitation position of SAWs is selective by sweeping in wide frequency ranges, allowing for the droplet position to be customized within the aperture region. We verify the reasonable existence of acoustic swirls in sessile droplets by a combination of simulations and experiments. The different periphery of the droplet meeting with SAWs will produce acoustic streaming phenomena with different intensities. The experiments demonstrate that acoustic swirls formed after SAWs encountering droplet boundaries will be more obvious. The acoustic swirls have strong stirring abilities to rapidly dissolve the yeast cell powder granules. Therefore, acoustic swirls are expected to be an effective means for rapid stirring of biomolecules and chemicals, providing a new approach to micro-stirring in biomedicine and chemistry. Full article
(This article belongs to the Special Issue Acoustofluidics for Chemical, Biological, and Medical Applications)
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