Wearable and Implantable Bio-MEMS Devices and Applications, 2nd Edition

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 1893

Special Issue Editor

Unmanned System Research Institue, Northwestern Polytechnical University, Xi’an 710072, China
Interests: flexible electronics; implantable devices; bio- and medical MEMS devices
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Wearable and implantable MEMS sensors and actuators have attracted tremendous attention in health monitoring, disease treatment, human–machine interaction, etc., due to their flexibility, minimization, low power consumption, and biocompatibility. A variety of devices have been developed in the last decade regarding the general aspects of advanced materials, device design, manufacturing, and packaging methods, as well as system integration.

This Special Issue focuses on the recent development and solution of wearable and implantable Bio-MEMS devices from the aspects of optimized design methods, micromachining technologies, and microsystem integration on any potential application. Specifically, the optimized design method includes the application of new biocompatible materials, theoretical calculation, and simulation; the micromachining technology focuses on the development of MEMS-fabricated devices based on either silicon or non-silicon materials to achieve better performance; microsystem integration should consider the packages, connection, miniaturization, failure modes, etc. In brief, wearable and implantable bio- and medical MEMS devices are expected to revolutionize personalized healthcare monitoring and precision therapy, and, thus, continued efforts to develop wearable and implantable devices and systems hold great promise for the quality of people’s lives. Any other topics related to bio- and medical MEMS are also welcome.

Dr. Bowen Ji
Guest Editor

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Keywords

  • wearable devices and systems
  • implantable devices and systems
  • design and simulation for bio- and medical MEMS devices
  • manufacturing for bio- and medical MEMS devices
  • bio- and medical MEMS applications
  • other bio- and medical MEMS

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Published Papers (2 papers)

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Research

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20 pages, 6672 KiB  
Article
Design and Testing of a Portable Wireless Multi-Node sEMG System for Synchronous Muscle Signal Acquisition and Gesture Recognition
by Xiaoying Zhu, Chaoxin Li, Xiaoman Liu, Yao Tong, Chang Liu and Kai Guo
Micromachines 2025, 16(3), 279; https://doi.org/10.3390/mi16030279 - 27 Feb 2025
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Abstract
Surface electromyography (sEMG) is an important non-invasive method used in muscle function assessment, rehabilitation and human–machine interaction. However, existing commercial devices often lack sufficient channels, making it challenging to simultaneously acquire signals from multiple muscle sites.In this acticle, we design a portable multi-node [...] Read more.
Surface electromyography (sEMG) is an important non-invasive method used in muscle function assessment, rehabilitation and human–machine interaction. However, existing commercial devices often lack sufficient channels, making it challenging to simultaneously acquire signals from multiple muscle sites.In this acticle, we design a portable multi-node sEMG acquisition system based on the TCP protocol to overcome the channel limitations of commercial sEMG detection devices. The system employs the STM32L442KCU6 microcontroller as the main control unit, with onboard ADC for analog-to-digital conversion of sEMG signals. Data filtered by analogy filter is transmitted via an ESP8266 WiFi module to the host computer for display and storage. By configuring Bluetooth broadcasting channels, the system can support up to 40 sEMG detection nodes. A gesture recognition algorithm is implemented to identify grasping motions with varying channel configurations. Experimental results demonstrate that with two channels, the Gradient Boosting Decision Tree (GBDT) algorithm achieves a recognition accuracy of 99.4%, effectively detecting grasping motions. Full article
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Review

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79 pages, 3684 KiB  
Review
Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology
by Vishnuram Abhinav, Prithvi Basu, Shikha Supriya Verma, Jyoti Verma, Atanu Das, Savita Kumari, Prateek Ranjan Yadav and Vibhor Kumar
Micromachines 2025, 16(5), 522; https://doi.org/10.3390/mi16050522 (registering DOI) - 28 Apr 2025
Abstract
Wearable and implantable BioMEMSs (biomedical microelectromechanical systems) have transformed modern healthcare by enabling continuous, personalized, and minimally invasive monitoring, diagnostics, and therapy. Wearable BioMEMSs have advanced rapidly, encompassing a diverse range of biosensors, bioelectronic systems, drug delivery platforms, and motion tracking technologies. These [...] Read more.
Wearable and implantable BioMEMSs (biomedical microelectromechanical systems) have transformed modern healthcare by enabling continuous, personalized, and minimally invasive monitoring, diagnostics, and therapy. Wearable BioMEMSs have advanced rapidly, encompassing a diverse range of biosensors, bioelectronic systems, drug delivery platforms, and motion tracking technologies. These devices enable non-invasive, real-time monitoring of biochemical, electrophysiological, and biomechanical signals, offering personalized and proactive healthcare solutions. In parallel, implantable BioMEMS have significantly enhanced long-term diagnostics, targeted drug delivery, and neurostimulation. From continuous glucose and intraocular pressure monitoring to programmable drug delivery and bioelectric implants for neuromodulation, these devices are improving precision treatment by continuous monitoring and localized therapy. This review explores the materials and technologies driving advancements in wearable and implantable BioMEMSs, focusing on their impact on chronic disease management, cardiology, respiratory care, and glaucoma treatment. We also highlight their integration with artificial intelligence (AI) and the Internet of Things (IoT), paving the way for smarter, data-driven healthcare solutions. Despite their potential, BioMEMSs face challenges such as regulatory complexities, global standardization, and societal determinants. Looking ahead, we explore emerging directions like multifunctional systems, biodegradable power sources, and next-generation point-of-care diagnostics. Collectively, these advancements position BioMEMS as pivotal enablers of future patient-centric healthcare systems. Full article
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