Microphysiological Systems for Cancer Research
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".
Deadline for manuscript submissions: 25 March 2025 | Viewed by 92
Special Issue Editor
Interests: microfluidics; cancer; microphysiological systems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microphysiological systems (MPS) are experimental platforms that mimic the physiological functions of human and animal organs and tissues in health and disease. MPS are incredibly versatile tools, given the small sample sizes required to operate them, the improved manipulation and sample control and overall, as á la carte models. FDA and NIH support in the US has helped drive the field and thus, MPS have come to the spotlight in recent years.
Many different MPS now exist, ranging from simple to highly sophisticated MPS and applications in different diseases continue to increase, with cancer being one of the most common applications. These models are now helping move the field of cancer research forward by allowing researchers to interrogate specific mechanisms, understand cell–cell and cell–environment interactions in the tumor niche, and recapitulate elusive microenvironments, such as metastatic sites, to better understand these processes and find new therapeutic targets.
In this Special Issue, we invite contributions (original research papers, review articles, and brief communications) that focus on the latest applications and advances in MPS in cancer research broadly, including new device development, novel applications of MPS both technologically and biologically oriented. We hope to provide an interesting update on current work in MPS in cancer that is of interest to both the engineering and biomedical community.
Dr. María Virumbrales-Muñoz
Guest Editor
Manuscript Submission Information
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Keywords
- MPS
- microfluidics
- tissue engineering
- cancer
- organoid
- migration
- mechanism
- interactions
- organ-on-a-chip
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