Pathogenesis, Virulence and Host Responses to Infections by Candida spp
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 33
Special Issue Editor
Interests: pathogenesis of opportunistic infections by Candida albicans and other fungi of the genus Candida; fungal biofilm; innate immunity to fungal infections
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Candida is a fungal genus including several species (such as C. albicans, C. glabrata, C. parapsilosis) that affect human health at various levels. In addition, the cognate genus Candidozyma, that includes the species Candidozyma auris (formerly known as Candida auris) is raising concerns due to its quick widespread, and to its high drug resistance profile that makes it difficult to treat, especially in hospital settings. This Special Issue of Microorganisms aims to gather and present new data concerning the virulence traits and pathogenetic mechanisms of Candida albicans, as well as other non-albicans Candida species. This Special Issue will also deal with the host responses to Candida infections, since it is well established that the pathogenesis of such infections results from a combination of fungal virulence and the way the immune system responds to the fungus. Indeed, the species Candida albicans is a member of the commensal microbiota, and as such, it interacts at various levels with the host cells and with other members of the microbiota. In certain conditions, C. albicans can shift to pathogenicity, and consequently, the host shifts from tolerance to an innocuous commensal to the triggering of an immune response against a dangerous pathogen. Another aspect linked to the pathogenesis of Candida spp. concerns the diagnosis and the antifungal treatment of these infections, which are still challenging aspects.
Original research, communications, and reviews covering all these topics will be welcomed.
Dr. Andrea Ardizzoni
Guest Editor
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Keywords
- Candida albicans
- Candida spp.
- pathogenetic mechanisms
- virulence traits
- fungal–host interactions
- diagnostics
- antifungal therapy
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