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Advancing Food Safety: Chemistry in Food Microbiology Control

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Food Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 619

Special Issue Editors


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Guest Editor
College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China
Interests: foodborne pathogens; rapid detection; real time PCR; bacteriophage; gene expression
Special Issues, Collections and Topics in MDPI journals
College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China
Interests: foodborne pathogens; biotoxin; nondestructive testing; gene expression; biocide

Special Issue Information

Dear Colleagues,

Microbes exist in the raw materials of processed and preserved food. Beneficial microorganisms confer food a special flavor, enhance its nutritional value, and prolong the preservation period. However, harmful microorganisms can cause the deterioration of the chemical properties and physical state of food and produce toxic and harmful substances, which may cause food safety problems. At present, foodborne diseases caused by pathogenic microorganisms represent a major public health concern worldwide and pose a serious threat to human health. Therefore, the effective utilization of beneficial microorganisms and the control of harmful microorganisms, including chemical sterilization technology and chemical detection technology, has become essential to ensuring the quality and safety of food.

This Special Issue aims to compile recent developments in microbial prevention and control in the field of food safety. The Special Issue aspires to expand our collective knowledge in the field of food microorganisms, presenting original innovative research and reviews. The scope of this Special Issue therefore includes, but is not limited to, the following:

  1. The utilization of chemical disinfectant and chemical sterilization technology to prevent and control  harmful microorganisms.
  2. Microbial risk assessment and safety monitoring, emphasizing the analytical techniques used to detect and quantify microbial contamination.
  3. The effect of microorganisms on the flavor quality of fermented foods, focusing on the chemical interactions and metabolic pathways that contribute to flavor compounds.
  4. The identification of harmful microbial factors and the elucidation of pathogenesis mechanisms at the molecular level, detailing the biochemical processes and toxic substances involved.

Dr. Shuai Wei
Dr. Qi Deng
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • foodborne pathogens
  • beneficial microorganisms
  • quality safety
  • risk assessment
  • safety monitoring

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Published Papers (1 paper)

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Research

13 pages, 1282 KiB  
Article
Molecular Mechanism: Inhibition of Fusarium oxysporum T-2 Toxin Synthesis by Surfactin in Dried Fish: Induction of Yap1 Nucleation by ROS Accumulation
by Qi Deng, Xueting Ren, Qin Hu, Yuehua Pu, Lukman Iddrisu, Anand Kumar, Meifang Hua, Jianmeng Liao, Zhijia Fang and Ravi Gooneratne
Molecules 2024, 29(22), 5402; https://doi.org/10.3390/molecules29225402 - 15 Nov 2024
Viewed by 353
Abstract
(1) T-2 toxin synthesized by Fusarium oxysporum (F. oxysporum) can cause deterioration of dried fish and endanger human health. (2) The molecular mechanism by which antibacterial lipopeptides surfactin inhibited F. oxysporum growth and toxin production was elucidated by investigating the intracellular [...] Read more.
(1) T-2 toxin synthesized by Fusarium oxysporum (F. oxysporum) can cause deterioration of dried fish and endanger human health. (2) The molecular mechanism by which antibacterial lipopeptides surfactin inhibited F. oxysporum growth and toxin production was elucidated by investigating the intracellular ROS production pathway and the subcellular distribution and transcriptional activity of the transcription factor Yap1 and its regulation of Tri5 gene in F. oxysporum. (3) Surfactin caused hyphal damage and nucleic acid and protein leakage; thus, the growth of F. oxysporum was disrupted. Surfactin’s excessive accumulation of intracellular ROS triggered the translocation of transcription factor Yap1 into the nucleus, resulting in toxin cluster gene Tri5 expression inhibition, thereby blocking T-2 toxin synthesis. (4) This is a novel mechanism by which surfactin inhibits the growth and T-2 toxin synthesis of F. oxysporum from multiple aspects, including cell structural integrity and the ROS-Yap1 signaling pathway. (5) This study provides a theoretical basis for the application of surfactin in the antifungal control of aquatic dry products. Full article
(This article belongs to the Special Issue Advancing Food Safety: Chemistry in Food Microbiology Control)
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