molecules-logo

Journal Browser

Journal Browser

Potential Antimicrobial Agents Occurred in Edible and Non-edible Plants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 941

Special Issue Editors


E-Mail Website
Guest Editor
1. Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina
2. Institute of Chemistry and Metabolism of Drugs (IQUIMEFA), University of Buenos Aires—National Scientific and Technical Research Council, Buenos Aires, Argentina
Interests: neglected diseases; antimicrobial activity; natural compounds; plant extracts; terpenoids; flavonoids; Asteraceae
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Bioorganic Chemistry Laboratory, Facultad de Ciencias Básicas y Aplicadas, Universidad Militar Nueva Granada, Campus Nueva Granada, Cajicá 250247, Colombia
Interests: natural product chemistry (isolation and structure elucidation); secondary/specialized metabolism; metabolic profiling; molecular modelling; docking and dynamics; bioorganic and medicinal chemistry; anti-parasitic, anti-cancer; anti-fungal; anti-inflammatory bioactive compounds
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Facultad de Ciencias Médicas, Instituto de Virología ‘Dr. J. M. Vanella’ Universidad Nacional de Córdoba, Córdoba, Argentina
Interests: neglected diseases; infectious diseases; antiviral activity; natural compounds; plant extracts; nanomolecules; native plants; domestication

E-Mail Website
Guest Editor
School of Biological Chemistry, Faculty of Chemical Science and Pharmacy, Universidad de San Carlos, Cdad. de Guatemala, Guatemala
Interests: ethnopharmacology; phytopharmacology

Special Issue Information

Dear Colleagues,

Throughout history and in recent years, infectious diseases caused by viruses, bacteria, parasites, and fungi have profoundly impacted human health, leading to significant economic and social consequences worldwide.  Many of these diseases caused by microorganisms have a high global incidence and lack effective and safe treatments.  Since ancient times, plants have played a crucial role in promoting human health, serving not only as foods and medicines but also as sources of novel active compounds and scaffolds for drug discovery.

Recently, the importance of certain edible plants has been highlighted, not only for their nutritional value but also for their potential as sources of active compounds, with a significant role in preventing and/or treating certain pathologies.  Functional foods contribute to reducing the incidence of diseases while enhancing biological defense mechanisms and the physical and mental well-being of individuals.

In this sense, this Special Issue aims to present research studies related to the antimicrobial activity of both edible and non-edible plants, as well as the natural compounds isolated from them.  Therefore, contributions (original research or review articles) focusing on the antimicrobial activity of plant-derived products (i.e., extracts, fractions), their effect on the immune system, as well as those related to the nutritional contribution of the edible plants, are particularly welcome.  We eagerly expect research contributions oriented to the in silico and/or in vitro evaluations of plant-derived compounds, their mechanism of action and/or target identification, as well as their potential applications in promoting human health and combating infectious diseases.  Additionally, the identification/recognition of antimicrobial active principles from edible and non-edible plants using traditional and emergent approaches, e.g., biological screening, bio-guided fractionation, high-throughput screening, microfractionation, and chemometrics/metabolomics, are also encouraged.  This Special Issue is part of the activities of the Potential Antimicrobial Agents present in Plant Foods of Regional Interest Network (REDALIM-MIC), which is affiliated with the Ibero-American Programme on Science and Technology (CYTED);  therefore, an emphasis on antimicrobial agents occurring in edible plants and plant foods is highly welcome.

Prof. Dr. Valeria Patricia Sülsen
Prof. Dr. Ericsson Coy-Barrera
Dr. Brenda Salomé Konigheim
Prof. Dr. Armando Caceres
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant extracts
  • natural compounds
  • infectious diseases
  • edible plants
  • medicinal plants

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 2922 KiB  
Article
Extracts and Terpenoids from Stevia Species as Potential Anthelmintics for Neglected Tropical Diseases Caused by Cestode Parasites
by María del Pilar Cevasco Contreras, Jimena Borgo, Ana María Celentano, Orlando Germán Elso, Hernán Bach, Cesar Atilio Nazareno Catalán, Augusto Ernesto Bivona, Hugo Rolando Vaca, Mara Cecilia Rosenzvit and Valeria Patricia Sülsen
Molecules 2024, 29(18), 4430; https://doi.org/10.3390/molecules29184430 - 18 Sep 2024
Viewed by 536
Abstract
Cestodes are etiological agents of neglected diseases such as echinococcosis and cysticercosis, which are major public health problems. Antiparasitic treatment relies on a small number of approved drugs, which are often only partially effective, poorly tolerated and require prolonged administration. Thus, the discovery [...] Read more.
Cestodes are etiological agents of neglected diseases such as echinococcosis and cysticercosis, which are major public health problems. Antiparasitic treatment relies on a small number of approved drugs, which are often only partially effective, poorly tolerated and require prolonged administration. Thus, the discovery of novel potential treatments is critical. The Stevia genus (Asteraceae) includes species that are recognized as a source of bioactive compounds, with many species associated with medicinal uses. In this study, the cestocidal activity of four South American Stevia species that previously showed antiprotozoal activity was analyzed using a motility assay on the laboratory cestode model, Mesocestoides vogae. The four Stevia extracts showed cestocidal activity, with S. alpina var. alpina as the most active. The sesquiterpene lactones estafietin and eupatoriopicrin were purified from S. alpina var. alpina and S. maimarensis, respectively, and tested on M. vogae. Estafietin showed cestocidal activity, inhibiting parasite viability in a dose-dependent manner, even from the first day of incubation. Consistent with the motility effects, the extract of S. alpina var. alpina and estafietin induced marked alterations in the morphology of the parasite. The results of this report show that Stevia species represent a source of new molecules with potential for the treatment of neglected tropical diseases caused by cestodes. Full article
Show Figures

Graphical abstract

Back to TopTop