Supramolecular Drug Delivery Based on Macrocycles
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 420
Special Issue Editor
Special Issue Information
Dear Colleagues,
Along with the booming of macrocycle-based host–guest chemistry studies in aqueous solutions, the diversity of supramolecular recognition systems has been greatly expanded, thus leading to the development of supramolecular assemblies that have potential applications in biological environments. Supramolecular drug delivery systems derived from host–guest complexation have contributed to the development of novel therapeutics in the past few decades. Macrocycle-based supramolecular assemblies possess the intrinsic stimuli responsiveness toward external guests or hosts, and a variety of other types of stimuli responsiveness, including pH, thermal, redox, photo, and enzyme, which can be further incorporated to realize multiple stimuli responsiveness. Host–guest chemistry can also mediate the supramolecular surface functionalization of drug delivery vehicles, to fabricate multifunctional drug delivery systems via a “Lego” way. This Special Issue aims to present innovative research regarding supramolecular drug delivery based on macrocycles and their derivatives, including but not limited to cyclodextrins, calixarenes, cucurbiturils, and pillararenes.
Dr. Shengke Li
Guest Editor
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Keywords
- supramolecular biomaterials
- macrocycles
- host–guest chemistry
- drug delivery
- stimuli responsiveness
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