molecules-logo

Journal Browser

Journal Browser

Discovery and Development of Targeted Anticancer Nanomedicines

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 1694

Special Issue Editor


E-Mail Website
Guest Editor
Institute of Medical Engineering, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an 710061, China
Interests: nanozymes; extracellular vesicles; drug delivery system; inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cancer is one of the most challenging diseases to treat and a global leading cause of death, and its related mortality is expected to rise to 13.1 million by 2030. Chemotherapy and radiation with non-selectivity limitations have led to the discovery and development of novel strategies for safe and effective cancer therapy treatment. Nanomedicine, as a potential area for cancer therapy, is used primarily as a source of nanocarriers or delivery agents for anticancer drugs due to its modulated biodistribution, its ability to protect medicines against degradation, and its ability to induce target-site accumulation of chemotherapeutic drugs, thereby reducing their toxicity. Furthermore, nanocarriers loaded with chemotherapeutic agents also overcome biological barriers such as renal and hepatic clearance, thus improving therapeutic efficacy. In addition, biomimetic nanomedicines coated with cell membrane can be used for targeted anticancer drug delivery thanks to their natural ability to target tumor cells.

In this Special Issue, we aim to highlight the importance of advanced nanomaterials and functional materials for targeted cancer therapy. We cordially invite authors to contribute original research articles, reviews, or shorter perspective articles on all aspects of the theme: “Discovery and Development of Targeted Anticancer Nanomedicines”. We especially welcome expert articles describing the potential of various nanomaterials for application in targeted cancer therapy, including their current state and clinical prospects.

Prof. Dr. Mingzhen Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer therapy
  • drug delivery systems
  • nanomaterials
  • nanomedicine
  • nanoparticle
  • nanotechnology
  • targeted therapy

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

20 pages, 11267 KiB  
Review
Ultrasound Sonosensitizers for Tumor Sonodynamic Therapy and Imaging: A New Direction with Clinical Translation
by Yunlong Liang, Mingzhen Zhang, Yujie Zhang and Mingxin Zhang
Molecules 2023, 28(18), 6484; https://doi.org/10.3390/molecules28186484 - 7 Sep 2023
Cited by 2 | Viewed by 1399
Abstract
With the rapid development of sonodynamic therapy (SDT), sonosensitizers have evolved from traditional treatments to comprehensive diagnostics and therapies. Sonosensitizers play a crucial role in the integration of ultrasound imaging (USI), X-ray computed tomography (CT), and magnetic resonance imaging (MRI) diagnostics while also [...] Read more.
With the rapid development of sonodynamic therapy (SDT), sonosensitizers have evolved from traditional treatments to comprehensive diagnostics and therapies. Sonosensitizers play a crucial role in the integration of ultrasound imaging (USI), X-ray computed tomography (CT), and magnetic resonance imaging (MRI) diagnostics while also playing a therapeutic role. This review was based on recent articles on multifunctional sonosensitizers that were used in SDT for the treatment of cancer and have the potential for clinical USI, CT, and MRI applications. Next, some of the shortcomings of the clinical examination and the results of sonosensitizers in animal imaging were described. Finally, this paper attempted to inform the future development of sonosensitizers in the field of integrative diagnostics and therapeutics and to point out current problems and prospects for their application. Full article
(This article belongs to the Special Issue Discovery and Development of Targeted Anticancer Nanomedicines)
Show Figures

Figure 1

Back to TopTop