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Advances in Organic Synthesis of Nitro Compounds and Their Derivatives

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1784

Special Issue Editors


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Guest Editor
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prosp., 119991 Moscow, Russia
Interests: nitro compounds; high nitrogen compounds; nitrogen heterocycles; energetic materials; nitration; novel synthetic methods

E-Mail Website
Guest Editor Assistant
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prosp., 119991 Moscow, Russia
Interests: nitro compounds; high nitrogen compounds; nitrogen heterocycles; energetic materials; novel synthetic methods; nitration; reaction mechanisms

E-Mail Website
Guest Editor Assistant
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prosp., 119991 Moscow, Russia
Interests: nitro compounds; high nitrogen compounds; nitrogen heterocycles; energetic materials; novel synthetic methods; reaction mechanisms; quantum-chemical calculations

Special Issue Information

Dear Colleagues,

The XIX century revealed the nitro group to the world. It was shown that its introduction into molecules turned ordinary cellulose into a highly effective propellant and harmless glycerin into one of the most famous energetic compounds and medicaments. Nitro dyes are well-known deeply colored substances, which have found wide industrial application. The XX century has become known as the time of unlocking the potential of the nitro group in different aspects, which has resulted in the appearance of new energetic materials, pharmaceutical drugs, antibiotics, anticorrosive materials, etc. The chemistry of nitro compounds remains one of the most active growing fields of organic chemistry at the present time, due to the diverse properties of the nitro group’s functionality, which provides nitro compounds with important roles as intermediates in organic synthesis. This Special Issue comprises a collection of original research and review articles that deal with the synthesis, chemistry, and applications of nitro-derivatives.

Prof. Dr. Vladimir A. Tartakovsky
Guest Editor

Dr. Michael S. Klenov
Dr. Alexey A. Voronin
Guest Editor Assistants

Manuscript Submission Information

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Keywords

  • nitro compounds
  • organic synthesis
  • cycloaddition
  • Michael acceptor
  • heterocycles
  • biologically active compounds
  • energetic materials
  • functional materials

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Published Papers (1 paper)

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Research

13 pages, 1952 KiB  
Article
Synthesis and Characterization of Azido- and Nitratoalkyl Nitropyrazoles as Potential Melt-Cast Explosives
by Elena Reinhardt, Tobias Lenz, Lukas Bauer, Jörg Stierstorfer and Thomas M. Klapötke
Molecules 2023, 28(18), 6489; https://doi.org/10.3390/molecules28186489 - 7 Sep 2023
Cited by 1 | Viewed by 1391
Abstract
Desirable advancements in the field of explosive materials include the development of novel melt-castable compounds with melting points ranging from 80 to 110 °C. This is particularly important due to the limited performance and high toxicity associated with TNT (trinitrotoluene). In this study, [...] Read more.
Desirable advancements in the field of explosive materials include the development of novel melt-castable compounds with melting points ranging from 80 to 110 °C. This is particularly important due to the limited performance and high toxicity associated with TNT (trinitrotoluene). In this study, a series of innovative melt-castable explosives featuring nitratoalkyl and azidoalkyl functionalities attached to the 3-nitro-, 4-nitro-, 3,4-dinitropyrazole, or 3-azido-4-nitropyrazole scaffold are introduced. These compounds were synthesized using straightforward methods and thoroughly characterized using various analytical techniques, including single-crystal X-ray diffraction, IR spectroscopy, multinuclear nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, elemental analysis, and DTA. Furthermore, the energetic properties such as (theoretical) performance data, sensitivities, and compatibilities of the compounds were evaluated and compared among the different structures. Full article
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