Analysis of Breath and Environment VOCs in Health and Disease
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 388
Special Issue Editors
Interests: mental health; biomarkers; neuroimaging; volatile organic compounds; proteomics
Special Issue Information
Dear Colleagues,
Neuropsychiatric disorders are increasingly recognized as leading causes of disease burden. The WHO estimates a 25% increase in mental disorders during the COVID-19 pandemic. Moreover, behavioral adaptation is needed in view of the climate crisis, a process that further poses a risk for mental health. To date, objective markers are not available, in particular for psychiatric disorders such as depression and schizophrenia, and there is a pressing need to identify biotypes in neuropsychiatric disorders that require different therapies. Nevertheless, signatures from the metabolome and microbiome have already been introduced as candidates for diagnostic and treatment support. A marker particularly applicable for psychiatric disorders is one that can be obtained noninvasively, without much discomfort for patients, and multiple times daily, if necessary. Recent developments are the introduction of breath gas measurements using mass spectrometry to identify volatile organic compounds (VOCs), as well as the investigation of the human microbiome or proteome analysis from blood. With respect to VOCs, these measurements can also capture signatures from the environment.
In this Special Issue, we aim to collect papers that address the identification of such markers in the field of neuropsychiatric disorders including, e.g., depression, PTSD, bipolar disorders, neurodegenerative disorders and stroke.
Prof. Dr. Thomas Frodl
Prof. Dr. Christoph Hoeschen
Guest Editors
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Keywords
- breath markers
- volatile organic compounds
- VOCs
- neuropsychiatric disorders
- mental health
- proteomics
- biotypes
- metabolomics
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