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Advances in the Application of Nanoparticles in Antimicrobial Research

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1161

Special Issue Editors


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Guest Editor
1. Department of Pharmaceutical Sciences, Faculty of Chemical Sciences, National University of Córdoba, Córdoba, Argentina
2. Pharmaceutical Technology Research and Development Unit, National Scientific and Technical Research Council (UNITEFA-CONICET), Córdoba, Argentina
Interests: nanobiomaterials; antimicrobial agents; biofilm eradication; sustainability
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Guest Editor
STEBICEF Department, University of Palermo, 90133 Palermo, Italy
Interests: luminescent nanoparticles; mesoporous silica materials; controlled release systems; polymeric nanocomposites; innovative materials for conservation of cultural heritage; non invasive methods
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanoparticles have shown promising advancements in antimicrobial research due to their unique properties and potential applications. These particles exhibit unique properties that enable them to effectively target and eradicate various types of pathogens, including bacteria, viruses, and fungi through mechanisms such as disrupting cell membranes, inhibiting biofilm formation, and enhancing drug delivery. Researchers are exploring innovative ways to utilize nanoparticles in antimicrobial coatings, medical devices, and drug delivery systems to enhance their efficacy against resistant microorganisms. The application of nanoparticles in antimicrobial research represents a growing field with significant potential to address the growing threat of antimicrobial resistance on One Health and chemistry frameworks with a collaborative, transdisciplinary, and multisectoral approach that promotes close cooperation across human health, animal health, agronomy, and the environment.

Prof. Dr. Paulina Laura Páez
Prof. Dr. Maria Luisa Saladino
Guest Editors

Manuscript Submission Information

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Keywords

  • nanoparticles
  • nanobiomaterials
  • antimicrobial activity
  • antimicrobial resistance
  • photodynamic antimicrobial therapy
  • innovation
  • drug delivery
  • sustainability

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Published Papers (1 paper)

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Research

19 pages, 3688 KiB  
Article
Structural, Morphological, and Antibacterial Attributes of Graphene Oxide Prepared by Hummers’ and Brodie’s Methods
by Vittorio Marsala, Yuriy Gerasymchuk, Maria Luisa Saladino, Emil Paluch, Magdalena Wawrzyńska, Vitalii Boiko, Xiang Li, Cristina Giordano, Dariusz Hreniak and Beata Sobieszczańska
Molecules 2025, 30(2), 240; https://doi.org/10.3390/molecules30020240 - 9 Jan 2025
Viewed by 1023
Abstract
Graphite oxidation to graphene oxide (GO) is carried out using methods developed by Brodie (GO-B) and Hummers (GO-H). However, a comparison of the antibacterial properties based on the physicochemical properties has not been performed. Therefore, this paper outlines a comparative analysis of GO-H [...] Read more.
Graphite oxidation to graphene oxide (GO) is carried out using methods developed by Brodie (GO-B) and Hummers (GO-H). However, a comparison of the antibacterial properties based on the physicochemical properties has not been performed. Therefore, this paper outlines a comparative analysis of GO-H and GO-B on antibacterial efficacy against Gram-positive and Gram-negative bacterial cultures and biofilms in an aqueous environment and discusses which of the properties of these GO nanomaterials have the most significant impact on the antibacterial activity of these materials. Synthesis of GO with Brodie’s and modified Hummers’ methods was followed by an evaluation of their structural, morphological, and physicochemical properties by Raman, FTIR, UV–vis spectroscopy, and X-ray diffraction (XRD). The GO-B surface appeared more oxidized than that of GO-H, which could be crucial for interactions with bacteria. According to our results, GO-B demonstrated notably superior anti-biofilm efficacy. Despite its higher production cost, GO-B exhibits more excellent capabilities in combating bacterial biofilms than GO-H. Full article
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