molecules-logo

Journal Browser

Journal Browser

Catalysis of Radical Reactions: Recent Progress and Emerging Fields

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 5237

Special Issue Editors


E-Mail Website
Guest Editor
Canadian Bank Note Company, 145 Richmond Rd, Ottawa, ON K1Z 1A1, Canada
Interests: radical chemistry; photoredox catalysis; alkylation; redox catalysis; tetrels

E-Mail Website
Guest Editor
1. Institute of Pharmaceutical Science and Technology, College of Chemistry, Fuzhou University, Fuzhou 350108, China
2. Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University, Fuzhou 350108, China
Interests: electrochemistry; transition metal catalysis; radical chemistry; asymmetric synthesis; heterocycles

Special Issue Information

Dear Colleagues,

With the call heard around the world of research, radical chemistry has become a mainstay field in the organic chemistry community. Having practical applications in academic and industrial settings, one-electron-based catalytic cross-coupling reactions have garnered intriguing levels of attention, reminiscent of the two-electron cross-coupling reactions, finding their fame due to Pd catalysis. Radical intermediates have traditionally received a bad rap, owing to their high reactivity and the assumption of uncontrolled reactivity. The catalysis of radical reactions has proven that the generation of radical intermediates using redox (photocatalytic, electrocatalytic, and organocatalytic), energy transfer, and atom transfer processes can be harnessed to achieve highly selective reactions under mild and controllable conditions. As our understanding of the fundamental reactivity of radical intermediates has matured, discovery and innovation have continued to flourish through the combination of novel radical and tradition catalytic approaches from the creative minds leading the field. This Special Issue seeks to highlight the remarkable advancements achieved in the catalysis of radical reactions with cutting-edge research articles and state-of-the-art reviews of emerging topics in the field.

Dr. Terry McCallum
Prof. Dr. Keyin Ye
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • radical chemistry
  • redox catalysis
  • electrocatalysis
  • photocatalysis
  • organic synthesis
  • asymmetric synthesis
  • transition metal catalysis
  • heterocycles

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

9 pages, 1492 KiB  
Communication
Paired Electrolysis Enabled Cyanation of Diaryl Diselenides with KSCN Leading to Aryl Selenocyanates
by Wei-Bao He, Luo-Lin Tang, Jun Jiang, Xiao Li, Xinhua Xu, Tian-Bao Yang and Wei-Min He
Molecules 2023, 28(3), 1397; https://doi.org/10.3390/molecules28031397 - 1 Feb 2023
Cited by 4 | Viewed by 1595
Abstract
The first example of paired electrolysis-enabled cyanation of diaryl diselenides, with KSCN as the green cyanating agent, has been developed. A broad range of aryl selenocyanates can be efficiently synthesized under chemical-oxidant- and additive-free, energy-saving and mild conditions. Full article
(This article belongs to the Special Issue Catalysis of Radical Reactions: Recent Progress and Emerging Fields)
Show Figures

Figure 1

10 pages, 1653 KiB  
Article
Metal-Free Aerobic C–N Bond Formation of Styrene and Arylamines via Photoactivated Electron Donor–Acceptor Complexation
by Duona Fan, Ahmed Sabri, Hiroaki Sasai and Shinobu Takizawa
Molecules 2023, 28(1), 356; https://doi.org/10.3390/molecules28010356 - 1 Jan 2023
Viewed by 1562
Abstract
This study processes a facile and green approach for the Markovnikov-selective hydroamination of styrene with naphthylamine through irradiation with UV LED light (365 nm) via an electron donor–acceptor complexation between naphthylamines and oxygen in situ. This protocol showcases the synthetic potential for aerobic [...] Read more.
This study processes a facile and green approach for the Markovnikov-selective hydroamination of styrene with naphthylamine through irradiation with UV LED light (365 nm) via an electron donor–acceptor complexation between naphthylamines and oxygen in situ. This protocol showcases the synthetic potential for aerobic C–N bond formation without using a metal catalyst and photosensitizer. Three naphthylamines were examined and afforded desired C–N bond formation product in moderate yield. Full article
(This article belongs to the Special Issue Catalysis of Radical Reactions: Recent Progress and Emerging Fields)
Show Figures

Figure 1

15 pages, 1722 KiB  
Article
Hybrid Silsesquioxane/Benzoate Cu7-Complexes: Synthesis, Unique Cage Structure, and Catalytic Activity
by Alexey N. Bilyachenko, Victor N. Khrustalev, Evgenii I. Gutsul, Anna Y. Zueva, Alexander A. Korlyukov, Lidia S. Shul’pina, Nikolay S. Ikonnikov, Pavel V. Dorovatovskii, Dmitri Gelman, Elena S. Shubina and Georgiy B. Shul’pin
Molecules 2022, 27(23), 8505; https://doi.org/10.3390/molecules27238505 - 3 Dec 2022
Cited by 7 | Viewed by 1586
Abstract
A series of phenylsilsesquioxane-benzoate heptacopper complexes 13 were synthesized and characterized by X-ray crystallography. Two parallel routes of toluene spontaneous oxidation (into benzyl alcohol and benzoate) assisted the formation of the cagelike structure 1. A unique multi-ligation of copper ions [...] Read more.
A series of phenylsilsesquioxane-benzoate heptacopper complexes 13 were synthesized and characterized by X-ray crystallography. Two parallel routes of toluene spontaneous oxidation (into benzyl alcohol and benzoate) assisted the formation of the cagelike structure 1. A unique multi-ligation of copper ions (from (i) silsesquioxane, (ii) benzoate, (iii) benzyl alcohol, (iv) pyridine, (v) dimethyl-formamide and (vi) water ligands) was found in 1. Directed self-assembly using benzoic acid as a reactant afforded complexes 23 with the same main structural features as for 1, namely heptanuclear core coordinated by (i) two distorted pentameric cyclic silsesquioxane and (ii) four benzoate ligands, but featuring other solvate surroundings. Complex 3 was evaluated as a catalyst for the oxidation of alkanes to alkyl hydroperoxides and alcohols to ketones with hydrogen peroxide and tert-butyl hydroperoxide, respectively, at 50 °C in acetonitrile. The maximum yield of cyclohexane oxidation products as high as 32% was attained. The oxidation reaction results in a mixture of cyclohexyl hydroperoxide, cyclohexanol, and cyclohexanone. Upon the addition of triphenylphosphine, the cyclohexyl hydroperoxide is completely converted to cyclohexanol. The specific regio- and chemoselectivity in the oxidation of n-heptane and methylcyclohexane, respectively, indicate the involvement of of hydroxyl radicals. Complex 3 exhibits a high activity in the oxidation of alcohols. Full article
(This article belongs to the Special Issue Catalysis of Radical Reactions: Recent Progress and Emerging Fields)
Show Figures

Figure 1

Back to TopTop