Mechanism of Anticancer Activity of Marine Natural Compounds
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (1 March 2022) | Viewed by 5048
Special Issue Editors
Interests: Structural elucidation; marine secondary metabolites; marine natural products; biological activities; cytotoxic mechanism; in vitro and in vivo assays
Special Issues, Collections and Topics in MDPI journals
Interests: apoptosis; cell culture; cancer biology; flow cytometry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Marine natural products have played a significant role in drug discovery for the last five decades. Secondary metabolites from marine organisms have proven to be highly effective in tackling the most serious health-threatening ailment of the twenty-first century: cancer. Drugs, such as Brentuximab vedotin, Cytarabine, Ara-C, Eribulin mesylate, and Trabectedin, have shown remarkable activity against a wide range of cancers. Other drugs are still in different clinical trial phases, showing promising results. Scientists all over the world are interested in isolating and identifying new anticancer secondary metabolites from novel marine sources. For any new entity to enter clinical trials, the full mechanism of action should be determined using in vitro and in vivo models.
In the current Special Issue, we are interested in original manuscripts and reviews discussing the anticancer mechanism of the action of secondary metabolites that are isolated from marine sources, including bacteria, fungi, sponges, algae, mangroves and coastal plants. We will also consider manuscripts focused on determining the anticancer mechanism of action for semisynthetic compounds of marine origin. By publishing in this Special Issue, scientists will highlight their research and promote their findings through the most widely read and respected journal on marine science.
Prof. Mei-Chin Lu
Prof. Mohamed El-Shazly
Guest Editors
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Keywords
- Mechanism of action of marine anticancer agents
- Anticancer secondary metabolites from sponge
- Algae secondary metabolites with anticancer activity
- Anticancer agents from marine bacteria
- Marine fungi as a source of anticancer agents
- Mangroves and coastal plants secondary metabolites with anticancer activity
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