Novel Heterocyclic Compounds in Drug Development
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 July 2022)
Special Issue Editors
Interests: organic synthesis; heterocyclic chemistry in drug discovery; medicinal chemistry; new synthetic methodologies; synthesis of new heterocyclic compounds
Special Issues, Collections and Topics in MDPI journals
Interests: organic synthesis; heterogeneous catalysis; heterocyclic chemistry; synthetic chemistry; organocatalysis; amide synthases
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute a full article, short communication, or review article to a Special Issue entitled “Novel Heterocyclic Compounds in Drug Development”. The issue aims to cover the most recent advances in organic chemistry and newly heterocyclic compounds and their potential role in medicinal chemistry.
Heterocyclic compounds are one of the largest and most varied classes of organic chemistry that are widespread in many natural compounds, with special attention in drug development. The heterocycle is a major class of organic compounds characterized by the presence of rings containing at least one atom of an element other than a carbon atom. The presence of the heteroatoms of nitrogen (N), oxygen (O), or sulfur (S) gives heterocyclic compounds quite distinct physical and chemical properties from those of other, different organic compounds.
Heterocyclic rings play an important role in biochemical processes, as they are one of the key elements of DNA, RNA, and coenzymes. They are present in many different pharmaceutical drugs exhibiting a broad range of biological activities including antimicrobial, anticancer, anticonvulsant, anti-HIV, anti-inflammatory, antioxidants, analgesic, antitubercular, and antimalarial agents.
We invite manuscript submissions of original research articles and reviews that discuss new bioactive heterocycle-containing compounds and their applications in medicinal chemistry, including design; synthesis; reactions; characterization of new chemical entities with therapeutic potential; structure elucidation; molecular modeling, and structure-activity relationships; pharmacokinetics investigation for new drugs; and the development of assays to assess therapeutic efficacy.
Dr. Youness El Bakri
Dr. Venkatanarayana Pappula
Dr. Heba E. Hashem
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- drug discovery
- new heterocyclic compounds
- new synthetic methodologies
- pharmaceutics
- medicinal agents synthesis
- biochemical mechanism
- natural product synthesis
- natural products including pharmacologically
