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Marine Bioinorganic and Bioorganic Chemistry

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 7203

Special Issue Editor


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Guest Editor
Department of Chemistry and Biochemistry, College of Sciences, San Diego State University, 5500 Campanile Avenue, San Diego, CA 92182-103, USA
Interests: bacterial–algal and bacterial–bacterial interactions; chemical communication; iron uptake and storage; the bioinorganic chemistry of other inorganic trace elements, including boron and the halogens, in the marine environment

Special Issue Information

Dear Colleagues,

The marine environment is an especially important one, given that the world’s oceans cover over 70% of the earth’s surface and was likely the birthplace of life as we know it, and is undergoing profound changes due to increased CO2 in the atmosphere. While marine bacteria and algae make up the vast majority of the oceans’ biomass and are the base of the oceanic food chain, the world’s oceans are also home to a wide range of invertebrates, many of which have yielded new and valuable natural products. These organisms not only mold and shape marine chemistry but are in turn affected by it and are thus a storehouse of unique and novel biomolecules whose structure, function, etc. can be very different from terrestrial counterparts.  This Special Issue aims at collecting original contributions and comprehensive reviews on topics such as the uptake, transport, and storage of trace elements in the marine environment as well as a determination of their functions, studies on novel marine metalloenzymes, their structures and mechanisms of action, the isolation, synthesis, and characterization of marine natural products, as well as studies of their function and biological roles, discovery of molecules involved in intra- and interspecies and/or kingdom communications, etc. These topics are meant to be broadly defined, the unifying factor being a marine origin. If you are working on any of these or related areas of marine chemistry, please consider contributing to this Special Issue.

Prof. Dr. Carl J. Carrano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Marine chemistry
  • Natural products
  • Trace elements
  • Metalloenzymes
  • Chemical communication
  • Isolation
  • Mechanisms of action
  • Biological role
  • Biosynthesis

Published Papers (2 papers)

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Research

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19 pages, 2990 KiB  
Article
1H NMR Metabolic Profile of Scyphomedusa Rhizostoma pulmo (Scyphozoa, Cnidaria) in Female Gonads and Somatic Tissues: Preliminary Results
by Federica Angilè, Laura Del Coco, Chiara Roberta Girelli, Lorena Basso, Lucia Rizzo, Stefano Piraino, Loredana Stabili and Francesco Paolo Fanizzi
Molecules 2020, 25(4), 806; https://doi.org/10.3390/molecules25040806 - 13 Feb 2020
Cited by 13 | Viewed by 2784
Abstract
The Mediterranean basin is one of the regions heavily affected by jellyfish bloom phenomena, mainly due to the presence of scyphozoans, such as Rhizostoma pulmo. The jellyfish have few natural predators, and their bodies represent an organic-rich substrate that can support rapid [...] Read more.
The Mediterranean basin is one of the regions heavily affected by jellyfish bloom phenomena, mainly due to the presence of scyphozoans, such as Rhizostoma pulmo. The jellyfish have few natural predators, and their bodies represent an organic-rich substrate that can support rapid bacterial growth with great impact on the structure of marine food webs. In Asiatic countries, jellyfish are widely studied for their health benefits, but their nutritional and nutraceutical values still remain poorly characterized. In this study, the differences in the 1H NMR spectroscopy metabolic profiles of R. pulmo female gonads and body fractions (including umbrella and oral arms), in different sampling periods, were studied. For each body compartment both lipid and aqueous extracts were characterized and their 1H NMR metabolic profiles subjected to multivariate analysis. From a statistical analysis of the extracts, a higher contents of ω-3 polyunsaturated fatty acids (PUFAs), amino acid and osmolytes (homarine, betaine, taurine) with important roles in marine invertebrates were observed in female gonads, whereas umbrella and oral arms showed similar metabolic profiles. These results support a sustainable exploitation of the jellyfish for the extraction of bioactive compounds useful in nutraceutical, nutricosmetics, and functional food fields. Full article
(This article belongs to the Special Issue Marine Bioinorganic and Bioorganic Chemistry)
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Review

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40 pages, 15100 KiB  
Review
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
by Claudio Luparello, Manuela Mauro, Valentina Lazzara and Mirella Vazzana
Molecules 2020, 25(11), 2471; https://doi.org/10.3390/molecules25112471 - 26 May 2020
Cited by 21 | Viewed by 3896
Abstract
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety [...] Read more.
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances under examination, grouping the producing species according to their taxonomic hierarchy. Taken all of the collected data into account, marine invertebrates emerge as a still poorly-exploited valuable resource of natural products that may significantly improve the process of skin regeneration and restrain tumor cell migration, as documented by in vitro and in vivo studies. Therefore, the identification of the most promising invertebrate-derived extracts/molecules for the utilization as new targets for biomedical translation merits further and more detailed investigations. Full article
(This article belongs to the Special Issue Marine Bioinorganic and Bioorganic Chemistry)
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