Bioactive Compounds and Chemical Analysis of Fruiting Bodies and Mycelial Cultures
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 9911
Special Issue Editors
Interests: medicinal mushrooms; mycelium cultures; bioactive compounds (non-hallucinogenic indole compounds, phenolic acids, triterpenes, sterols); use of mushrooms in cosmetology
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal mushrooms; secondary metabolites of mushrooms; biological activity of mushrooms: anti-inflammatory, neuroprotective, immunostimulatory; prebiotics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biotechnological solutions for the acquisition of medicinal, health-promoting, and cosmetic substances occupy an important place in the global pharmaceutical, cosmetic and health-food industries. A significant share in these solutions is related to the biotechnology of higher fungi, including medicinal species. An important research direction in the biotechnology of higher fungi is the endogenous production of bioactive compounds by biomass from mycelial cultures. Secondary metabolites produced by mycelial cultures representing various chemical groups are characterized by multidirectional biological activity, including antioxidant, immunostimulatory, antitumor, anti-inflammatory, and antimicrobial - including antiviral activity. Mycelial cultures are a good model of research on natural raw material due to the short time of pure biomass cultivation. Mycelial cultures can be run under highly reproducible conditions, resulting in a constant composition of the obtained biomass. The possibility of optimizing the composition of the culture medium may increase the efficiency of biosynthesis of biologically active compounds.
The research results presented in the Special Issue: Chemical Analysis of Mycelial Cultures will allow us to determine the biosynthetic capacity of mycelium obtained in vitro. On the one hand, they will help determine whether in vitro cultures retain the ability to synthesize similar metabolites found in fruiting bodies. On the other hand, they will answer the question of whether in vitro cultures can produce, under the influence of modified conditions, new compounds not present in fruiting bodies.
Dr. Katarzyna Sułkowska-ZiajaProf. Dr. Bożena Muszyńska
Guest Editors
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Keywords
- Mycelial cultures
- Secondary metabolites
- Terpenoids
- Biological activity
- Anticancer activity
- Antimicrobial activity
- Immunology
- Inflammation
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