Potential Application of Peptide Nucleic Acid in Biomedical Domain
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 789
Special Issue Editors
Interests: antimicrobial drug discovery and development; medicinal chemistry; peptides and peptidomimetics; unnatural amino acids; fluorescent probes; peptide nucleic acids; anticancer drug discovery; phenotypic drug discovery; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; nucleic acid based therapeutics; gene editing; nanotechnology; drug delivery; peptide nucleic acids; miRNA and cancer therapeutics
Special Issue Information
Dear Colleagues,
The aim of this Special Issue of Molecules is to publish a series of articles to emphasize the high interest in peptide nucleic acids (PNAs) in biomedical research. PNAs are synthetic DNA/RNA mimics in which the phosphodiester backbone is substituted with a neutral N-(2-aminoethyl) glycine backbone. Due to the neutral backbone, PNAs are resistant to enzymatic degradation and can bind to genomic DNA and RNA with high affinity. Due to high stability and improved selectivity, PNA has attracted the attention of many researchers for studying varying applications in synthetic chemistry, diagnostics, molecular biology and medicine, gene editing, etc. PNAs are emerging as powerful tools for various biomedical areas such as drug discovery, diagnostics, chemical biology, biotechnology, nanotechnology, etc.
This Special Issue can help researchers across the globe to publish their original research or review articles. Review articles by experts in this field are also welcome to focus on highlights and recent updates. Therefore, we invite academic and industrial investigators working in all related fields to submit original research articles or reviews describing and discussing the recent advancements, challenges, and developments of PNA in biomedical applications. We believe this Special Issue will be of interest to a wide range of researchers working on addressing the challenges and advancement of PNA in biomedical research.
Dr. Krishna K. Sharma
Dr. Anisha Gupta
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Recent advancements of peptide nucleic acids as therapeutic agents
- Recent advancements of peptide nucleic acids as diagnostic agents
- Synthesis of peptide nucleic acids
- Backbone modified peptide nucleic acids
- Various applications of peptide nucleic acids
- Recent advances of peptide nucleic acids for nanotechnology
- Peptide nucleic acids in drug delivery
- Peptide nucleic acids in bioconjugation
- Reviews highlighting specific biomedical applications
