Proteomics Progress in Cancer Research
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: closed (1 March 2022) | Viewed by 8574
Special Issue Editors
Interests: extracellular vesicles; exosomes; urine; biological fluids; membrane proteins; renal cell carcinoma; renal diseases; proteomics; lipidomics; glycoproteomics
Special Issue Information
Dear Colleagues,
Proteomics has shown to be a promising approach for understanding the etiopathogenesis of cancers, and for identifying potential biomarkers and therapeutic targets. Proteomic approaches allow an all-round study of proteins considering not only their quantitative expression but also the complex post-translational modifications (glycosylation, phosphorylation, etc.) and the protein–protein interactions, fundamental for functional understandings. Proteomics provides a variety of technologies that can be applied to different type of samples, from patient tissues to biological fluids and from cultured cells to animal models, through to extracellular vesicles and the tumor microenvironment. The combined study of different samples may allow the improvement of the knowledge of the dynamic biology of a specific cancer system. Moreover, the integration of proteomics into multi-omics studies could open the way for the rapid translation of laboratory discoveries to the bedside, having a positive impact on the clinical management and outcomes of cancer patients.
The present Special Issue on “Proteomics Progress in Cancer Research” welcomes articles reporting original discoveries, technical improvements and reviews in the field of cancer proteomics research, with an emphasis on the use of different sample types and data integration.
Dr. Francesca Raimondo
Prof. Marina Pitto
Guest Editors
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Keywords
- biological fluids
- cancer
- cultured cells
- extracellular vesicles
- multi-omics
- post-translational modifications
- proteomics
- tissues
- tumor microenvironment
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