Proteasome Regulators: Activators and Inhibitors
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 June 2019) | Viewed by 28402
Special Issue Editor
Special Issue Information
Dear Colleagues,
We are pleased to announce that submissions for the Molecules Special Issue "Proteasome Regulators: Activators and Inhibitors" are now open.
FDA (Food and Drug Administration) approval of the proteasome inhibitors bortezomib and carfilzomib (as well as ixazomib for some patients) as front-line therapy for multiple myeloma and mantle cell lymphoma has validated the proteasome as an important therapeutic target. Following that breakthrough, new research has illuminated other methods of proteasome regulations that have the potential to expand its therapeutic applications.
This Special Issue will focus on new directions in proteasome regulation including proteasome activation and alternative methods of inhibiting its proteolytic activity by small molecules. Original research articles as well as reviews that are able to make substantial advances in this field are welcome.
Dr. Jetze J. Tepe
Guest Editor
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