Applications of Nanoparticles for anti-(Cancer Drug Delivery, Bacterial Activity) and SERS Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (20 December 2023) | Viewed by 1780

Special Issue Editors

Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China
Interests: graphene; biosensor; field-effect transistor; SERS; SPR; fluorescence biosensor; electrochemiluminescence
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China
Interests: nanoparticles for antibcancer drug delivery and antibacterial activity

E-Mail Website
Guest Editor
Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China
Interests: SERS; nanomaterials

Special Issue Information

Dear Colleagues,

Nanoparticles have emerged as a promising tool in various fields of biomedical research due to their unique physical, chemical, and biological properties. This Special Issue aims to explore the current state-of-the-art research on the applications of nanoparticles in anticancer drug delivery, antibacterial activity, and sensors.

Anticancer drug delivery: Nanoparticles have been extensively studied for their potential use in targeted drug delivery for cancer therapy. Various types of nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, have been developed and tested for their efficacy in delivering anticancer drugs to tumor cells. The use of nanoparticles for drug delivery has shown promising results in improving the pharmacokinetics and bioavailability of anticancer drugs, reducing toxicity, and enhancing the therapeutic effect.

Antibacterial activity: Nanoparticles have also shown potential as antibacterial agents due to their ability to disrupt bacterial membranes and inhibit bacterial growth. Silver nanoparticles, for example, have been extensively studied for their antibacterial activity against a wide range of bacterial strains. Other nanoparticles such as gold, zinc oxide, and copper oxide have also been investigated for their antibacterial properties.

Nanostructured materials for SERS applications: Surface-enhanced Raman scattering (SERS) has emerged as a powerful spectroscopic technique for ultrasensitive detection and the identification of various molecules. In recent years, SERS has attracted significant attention due to its exceptional sensitivity, reproducibility, and selectivity. The performance of SERS is highly dependent on the properties of the substrate used. Thus, the development of efficient SERS substrates with high sensitivity and reproducibility is of great interest in the field of nanotechnology.

In conclusion, this Special Issue highlights the potential applications of nanoparticles in anticancer drug delivery and antibacterial activity. This issue will also cover applications of nanostructured SERS substrates in bio/chemical sensing, imaging, and environmental monitoring. The development of novel nanoparticles and their application in various fields of biomedical research holds great promise for the future of medicine and biotechnology.

Dr. Shicai Xu
Dr. Naif M. Al-Hada
Dr. Chonghui Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metal oxide nanoparticles
  • anticancer drug delivery
  • antibacterial activity
  • metal nanoparticles
  • binary oxide nanoparticles
  • bimetallic nanoparticles
  • SERS applications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

15 pages, 2956 KiB  
Article
Antifungal Effect of Polymethyl Methacrylate Resin Base with Embedded Au Nanoparticles
by Ivan Marić, Anamarija Zore, Franc Rojko, Andrijana Sever Škapin, Roman Štukelj, Aleksander Učakar, Rajko Vidrih, Valentina Veselinović, Marijan Gotić and Klemen Bohinc
Nanomaterials 2023, 13(14), 2128; https://doi.org/10.3390/nano13142128 - 22 Jul 2023
Cited by 2 | Viewed by 1462
Abstract
Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how [...] Read more.
Full and partial restorations in dentistry must replicate the characteristics of the patient’s natural teeth. Materials must have good mechanical properties and be non-toxic and biocompatible. Microbes, which can form biofilms, are constantly in contact with restorations. In this study, we investigate how well Candida albicans adheres to a polymethyl methacrylate (PMMA) resin base with gold (Au) nanoparticles. We synthesized Au nanoparticles and characterized them. The average size of Au nanoparticles embedded in PMMA was 11 nm. The color difference ΔE between PMMA and PMMA/Au composites was 2.7 and was still esthetically acceptable to patients. PMMA/Au surfaces are smoother and more hydrophilic than pure PMMA surfaces, and the isoelectric point of both types of surfaces was 4.3. Above the isoelectric point, PMMA/Au surfaces are more negatively charged than PMMA surfaces. The added Au nanoparticles decreased the tensile strength, while the hardness did not change significantly. Adhesion measurements showed that PMMA surfaces modified with Au nanoparticles reduced the extent of microbial adhesion of Candida albicans. Full article
Show Figures

Figure 1

Back to TopTop